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Semantic Search: Fwd: many skin creams don’t work
Fwd: many skin creams don’t work
Score 0.824
· Account tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z ---------- Forwarded message ---------- From: Blueprint <hello@bryanjohnson.com> Date: Mar 26, 2026 at 2:03 PM -0400 To: tjphuhs@gmail.com Subject: many skin creams don’t work > ingredients to look for ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
Fwd: many skin creams don’t work
Score 0.824
· Account oc.tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z ---------- Forwarded message ---------- From: Blueprint <hello@bryanjohnson.com> Date: Mar 26, 2026 at 2:03 PM -0400 To: tjphuhs@gmail.com Subject: many skin creams don’t work > ingredients to look for ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
Fwd: many skin creams don’t work
Score 0.756
· Account tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z Blueprint or elsewhere, pay close attention to the ingredients. > > 3 skincare actives to look for > > 1. SFC (Disodium Succinoyl Farnesylcysteine) is a novel compound that supports healthy inflammatory balance, showing improvements compared to niacinamide, the leading active in most creams. > > In a clinical trial, 1% SFC statistically outperformed 5% niacinamide at reducing visible wrinkles, improving texture,
Fwd: many skin creams don’t work
Score 0.756
· Account oc.tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z Blueprint or elsewhere, pay close attention to the ingredients. > > 3 skincare actives to look for > > 1. SFC (Disodium Succinoyl Farnesylcysteine) is a novel compound that supports healthy inflammatory balance, showing improvements compared to niacinamide, the leading active in most creams. > > In a clinical trial, 1% SFC statistically outperformed 5% niacinamide at reducing visible wrinkles, improving texture,
Fwd: many skin creams don’t work
Score 0.749
· Account oc.tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z you think of this email? > *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. > Manage Preferences > No longer want to receive these emails? Unsubscribe > > 5042 Wilshire Blvd #26878 Los Angeles, CA 90036 | Privacy Policy >
Fwd: many skin creams don’t work
Score 0.749
· Account tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z you think of this email? > *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. > Manage Preferences > No longer want to receive these emails? Unsubscribe > > 5042 Wilshire Blvd #26878 Los Angeles, CA 90036 | Privacy Policy >
Fwd: many skin creams don’t work
Score 0.730
· Account tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z making these products overpromise. Few are based upon evidence. Fewer do anything. > > We reviewed the scientific evidence and found the actives we wanted. But the perfect anti-aging stack didn’t exist. So we built it. > > In this email: > > • + what causes skin aging > + how to slow visible signs of it > + skincare ingredients to look for > > What causes skin aging? > > Skin begins to age in your 20s: > > • + co
Fwd: many skin creams don’t work
Score 0.730
· Account oc.tjphuhs@gmail.com
· 3/26/2026, 2:05:09 PM
Fwd: many skin creams don’t work from tjphuhs@gmail.com on 2026-03-26T18:05:09.000Z making these products overpromise. Few are based upon evidence. Fewer do anything. > > We reviewed the scientific evidence and found the actives we wanted. But the perfect anti-aging stack didn’t exist. So we built it. > > In this email: > > • + what causes skin aging > + how to slow visible signs of it > + skincare ingredients to look for > > What causes skin aging? > > Skin begins to age in your 20s: > > • + co
many skin creams don’t work
Score 0.717
· Account tjphuhs@gmail.com
· 3/26/2026, 2:03:54 PM
many skin creams don’t work from hello@bryanjohnson.com on 2026-03-26T18:03:54.000Z [Blueprint Homepage](https://blueprint.bryanjohnson.com) Hi friend, Many skin creams don’t work. Bryan has experimented with dozens. In his experience, the companies making these products overpromise. Few are based upon evidence. Fewer do anything. We reviewed the scientific evidence and found the actives we wanted. But the perfect anti-aging stack didn’t exist. So we built it. In this email: - + what causes skin
many skin creams don’t work
Score 0.713
· Account tjphuhs@gmail.com
· 3/26/2026, 2:03:54 PM
many skin creams don’t work from hello@bryanjohnson.com on 2026-03-26T18:03:54.000Z on a skincare routine. Whether you’re getting your skincare stack from Blueprint or elsewhere, pay close attention to the ingredients. 3 skincare actives to look for - SFC (Disodium Succinoyl Farnesylcysteine) is a novel compound that supports healthy inflammatory balance, showing improvements compared to niacinamide, the leading active in most creams. In a clinical trial, 1% SFC statistically outperformed 5% nia
many skin creams don’t work
Score 0.696
· Account tjphuhs@gmail.com
· 3/26/2026, 2:03:54 PM
many skin creams don’t work from hello@bryanjohnson.com on 2026-03-26T18:03:54.000Z Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. [Manage Preferences](https://manage.kmail-lists.com/subscriptions/update?a=UDtiqU&c=01KJT9DP2RVS1CVFD3BD75ZESG&k=45025595cf22049e7e57727e73cdc99b&m=01KKVPGQ4N60PKACSGSSAVHT0E&r=01KMNMWCFKCM43HN0R51C1B9SE) No longer want to receive these emails? [Unsubscribe](https://manage.kmail-lists.com/subscriptions/uns
Fwd: When Ozempic stops working (and what 10% of users already know)
Score 0.641
· Account tjphuhs@gmail.com
· 3/17/2026, 2:05:41 PM
Fwd: When Ozempic stops working (and what 10% of users already know) from tjphuhs@gmail.com on 2026-03-17T18:05:41.000Z TJ Begin forwarded message: From: Seed Oil Scout <newsletter@seedoilscout.com> Date: March 17, 2026 at 1:36:08 PM EDT To: tjphuhs@gmail.com Subject: When Ozempic stops working (and what 10% of users already know) 96 The non-responder problem, the plateau trap, and the side effects pharma buries in the fine print. ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds
Score 0.638
· Account tjphuhs@gmail.com
· 3/17/2026, 2:42:07 PM
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds from tjphuhs@gmail.com on 2026-03-17T18:42:07.000Z of that, the functional impact is minimal. MT2 produces the same tanning effect, plus appetite suppression that some research subjects find significant, plus pro-erectile and libido-related effects driven by MC4R activity. You’re essentially getting multiple systems activated from a single compound. The tradeoff is side effects. Nausea with MT2 is common, particularly
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds
Score 0.638
· Account oc.tjphuhs@gmail.com
· 3/17/2026, 2:42:07 PM
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds from tjphuhs@gmail.com on 2026-03-17T18:42:07.000Z of that, the functional impact is minimal. MT2 produces the same tanning effect, plus appetite suppression that some research subjects find significant, plus pro-erectile and libido-related effects driven by MC4R activity. You’re essentially getting multiple systems activated from a single compound. The tradeoff is side effects. Nausea with MT2 is common, particularly
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research?
Score 0.628
· Account tjphuhs@gmail.com
· 3/26/2026, 11:40:30 AM
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research? from tjphuhs@gmail.com on 2026-03-26T15:40:30.000Z logic to including them. The issue is cost. Running BPC-157 and TB-500 as part of a year-round skin protocol is expensive, and the incremental benefit over GHK-Cu alone likely doesn’t justify it for most research purposes. GHK-Cu is the primary driver. BPC and TB-500 are a nice addition for an acute phase, not a staple. > If the RS has healthy skin with no inf
Fwd: When Ozempic stops working (and what 10% of users already know)
Score 0.628
· Account tjphuhs@gmail.com
· 3/17/2026, 2:05:41 PM
Fwd: When Ozempic stops working (and what 10% of users already know) from tjphuhs@gmail.com on 2026-03-17T18:05:41.000Z to lose even 5% of body weight, the minimum threshold considered clinically meaningful. In the SURMOUNT-2 trial for tirzepatide, 17-21% of participants didn't hit that 5% mark. Why? Variants in the GLP-1 receptor gene affect how strongly the drug signals satiety. Gut microbiome composition also influences response. And if your metabolism is already adapted to caloric restrictio
Results from my Feb 23 skin therapy:
Score 0.622
· Account tjphuhs@gmail.com
· 4/6/2026, 8:42:28 PM
Results from my Feb 23 skin therapy: from bryanjohns0n@substack.com on 2026-04-07T00:42:28.000Z View this post on the web at https://bryanjohns0n.substack.com/p/results-from-my-feb-23-skin-therapy Improvements since treatment: > Brown spots: +71 percentile points (20th → 91st)✅ > Pores: +25 percentile points✅ > Spots: +25 percentile points✅ My skin age is 9 years younger than my chronological age (39 vs 48) and hasn’t aged in five years since starting this project. Effectively a 9 year age rever
Dee Bougie posted "NEW REJURAN Product - Rejuran Healer "
Score 0.613
· Account tjphuhs@gmail.com
· 3/9/2026, 7:05:33 PM
Dee Bougie posted "NEW REJURAN Product - Rejuran Healer " from noreply@skool.com on 2026-03-09T23:05:33.000Z commonly referred to as 婴儿针 (Baby Skin Injection), is designed to activate your skin’s regenerative capabilities using PN (polynucleotide) molecules derived from salmon DNA<img height="0" width="0"/>.<br/><br/>Unlike hyaluronic acid-based skin booster, this formulation helps repair damaged skin cells, stimulate collagen production, and improve elasticity over time<img height="0" width="0"
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research?
Score 0.610
· Account tjphuhs@gmail.com
· 3/26/2026, 11:40:30 AM
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research? from tjphuhs@gmail.com on 2026-03-26T15:40:30.000Z need to make the right call for your RS. > First up: the two most popular blends in the research space right now — GLOW and KLOW. Let’s get into it. > Upgrade to paid > What’s in these blends? > GLOW = GHK-Cu + BPC-157 + TB-500 KLOW = GHK-Cu + BPC-157 + TB-500 + KPV > Typical ratios you’ll see: 50 mg GHK-Cu / 10 mg BPC-157 / 10 mg TB-500 / 10 mg KPV > At first
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds
Score 0.609
· Account tjphuhs@gmail.com
· 3/17/2026, 2:42:07 PM
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds from tjphuhs@gmail.com on 2026-03-17T18:42:07.000Z as synthetic analogs of alpha-melanocyte stimulating hormone — α-MSH — a naturally occurring peptide your body already produces. α-MSH plays a central role in regulating pigmentation, appetite, inflammation, and sexual function by binding to a family of receptors called melanocortin receptors (MC1R through MC5R). The researchers weren’t trying to create a tanning pept
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds
Score 0.609
· Account oc.tjphuhs@gmail.com
· 3/17/2026, 2:42:07 PM
Fwd: Melanotan 1 vs Melanotan 2: Same Starting Point, Very Different Compounds from tjphuhs@gmail.com on 2026-03-17T18:42:07.000Z as synthetic analogs of alpha-melanocyte stimulating hormone — α-MSH — a naturally occurring peptide your body already produces. α-MSH plays a central role in regulating pigmentation, appetite, inflammation, and sexual function by binding to a family of receptors called melanocortin receptors (MC1R through MC5R). The researchers weren’t trying to create a tanning pept
Fwd: When Ozempic stops working (and what 10% of users already know)
Score 0.605
· Account tjphuhs@gmail.com
· 3/17/2026, 2:05:41 PM
Fwd: When Ozempic stops working (and what 10% of users already know) from tjphuhs@gmail.com on 2026-03-17T18:05:41.000Z Rate Problem Retatrutide is Eli Lilly's triple agonist (GIP/GLP-1/glucagon). Early results: up to 24.2% weight loss at 48 weeks per the NEJM Phase 2 trial. But buried in the data: dose-dependent increases in heart rate peaking at 24 weeks. The glucagon receptor component is the likely culprit. At the 12mg dose, heart rate elevations were clinically notable. Users report resting
Fwd: Stuck on Reta?
Score 0.603
· Account oc.tjphuhs@gmail.com
· 5/9/2026, 1:49:02 PM
Fwd: Stuck on Reta? from tjphuhs@gmail.com on 2026-05-09T17:49:02.000Z why I personally only use MT1, why MT2 is more like a tanning bed (use it for an event, not year-round), and how I think about the cancer question for each one. There's also a tangent about tanning beds in the early 2000s that probably explains a lot about a generation of skin issues. > > Perimenopausal Sleep Problems > This is one of the biggest topics we get asked about. One listener was on MK-677, sleeping great, but binge
Fwd: Stuck on Reta?
Score 0.603
· Account tjphuhs@gmail.com
· 5/9/2026, 1:49:02 PM
Fwd: Stuck on Reta? from tjphuhs@gmail.com on 2026-05-09T17:49:02.000Z why I personally only use MT1, why MT2 is more like a tanning bed (use it for an event, not year-round), and how I think about the cancer question for each one. There's also a tangent about tanning beds in the early 2000s that probably explains a lot about a generation of skin issues. > > Perimenopausal Sleep Problems > This is one of the biggest topics we get asked about. One listener was on MK-677, sleeping great, but binge
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research?
Score 0.602
· Account tjphuhs@gmail.com
· 3/26/2026, 11:40:30 AM
Fwd: Breaking Down the Blend: Does GLOW or KLOW Actually Make Sense for Your Research? from tjphuhs@gmail.com on 2026-03-26T15:40:30.000Z support collagen remodeling acutely but are not cost-effective year-round > • > Skip KPV unless there’s a specific inflammatory component to address > > Skin research (rosacea, eczema, chronic inflammation) > > • > GHK-Cu + KPV is the targeted approach — the blend that just came out is built for exactly this > • > Same cost consideration applies to BPC/TB-500