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---------- Forwarded message ----------
From: Blueprint <hello@bryanjohnson.com>
Date: Mar 26, 2026 at 2:03 PM -0400
To: tjphuhs@gmail.com
Subject: many skin creams don’t work
> ingredients to look for ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
> Hi friend,
>
> Many skin creams don’t work.
>
> Bryan has experimented with dozens. In his experience, the companies making these products overpromise. Few are based upon evidence. Fewer do anything.
>
> We reviewed the scientific evidence and found the actives we wanted. But the perfect anti-aging stack didn’t exist. So we built it.
>
> In this email:
>
> • + what causes skin aging
> + how to slow visible signs of it
> + skincare ingredients to look for
>
> What causes skin aging?
>
> Skin begins to age in your 20s:
>
> • + collagen and elastin decline: starting in our mid 20s, collagen content decreases by about 1% annually, reducing skin firmness and suppleness. Elastin, which provides stretchability and prevents wrinkling, also deteriorates over time.
>
> + loss of hydration: aging skin loses moisture due to changes in collagen, reduced hyaluronic acid content, and declines in skin lipid content. This leads to dryness, reduced thickness, and diminished suppleness.
>
> + environmental damage: chronic exposure to environmental factors, especially UV radiation and air pollutants, accelerates skin aging by breaking down collagen and inducing oxidative stress.
>
> + cellular aging: fibroblasts, responsible for collagen and hyaluronic acid production, become less efficient, impairing skin repair and water retention.
>
> How to slow visible signs of skin aging
>
> First, get the basics right: cleanse, hydrate, and keep inflammation and cellular damage at bay.
>
> Here is the basic protocol to maintain healthy skin:
>
> • + exercise
> + prioritize sleep
> + eat healthy
> + avoid junk, fried, or highly processed foods, cigarettes, and vaping
>
> Most importantly, limit UV exposure. Up to 90% of visible skin aging is from day-to-day sun exposure… not sunburn.
>
> UV and photoaging tips
>
> • + limit sun exposure to early mornings and later afternoons when the UV index is low.
> + when the UV index is high (10am - 4pm), protect your skin (SPF, a UV umbrella, hat, or clothing).
>
> Once you’ve mastered the basics, you can layer on a skincare routine. Whether you’re getting your skincare stack from Blueprint or elsewhere, pay close attention to the ingredients.
>
> 3 skincare actives to look for
>
> 1. SFC (Disodium Succinoyl Farnesylcysteine) is a novel compound that supports healthy inflammatory balance, showing improvements compared to niacinamide, the leading active in most creams.
>
> In a clinical trial, 1% SFC statistically outperformed 5% niacinamide at reducing visible wrinkles, improving texture, hydration, radiance, luminosity, and brightness, as well as improving the overall healthy appearance of the skin.
>
> 2. NMN (Nicotinamide Mononucleotide) is an NAD+ precursor. It has been studied for its role in cellular energy and healthy aging pathways. In skincare formulations, it may help support the skin barrier and antioxidant defenses
>
> 3. hyaluronic acid retains moisture, granting the skin extra firmness and an improved texture.
>
> The Blueprint skincare stack
>
> We based our 3-step skincare stack on these three ingredients plus additional longevity supermolecules.
>
> The science-backed benefits include:
>
> 1. longevity: helps defend against daily stressors that accelerate visible aging
>
> 2. firmness: helps maintain visibly firmer, smoother-looking skin
>
> 3. resilience: supports the skin barrier with humectants and emollients to protect and replenish
>
> 4. hydration: nourishes dry skin with sodium hyaluronate and amino acids for a deep, lasting moisture-rich appearance
>
> 5. protection: advanced antioxidants help defend against environmental stressors, improving the appearance of texture and redness
>
> Here’s how Bryan and Kate, Blueprint co-founders, use the stack:
>
> • + step 1: massage the Gentle Facial Cleanser into damp skin, rinse with lukewarm water to remove dirt, oil, makeup, and sunscreen without stripping the skin barrier.
> •
> + step 2: apply SFC Facial Serum to dry skin and let it absorb to help reduce the appearance of redness and irritation, and support the appearance of visible collagen production.
> •
> + step 3: massage the SFC Facial Moisturizer into clean, dry skin to help hydrate, firm, and replenish.
>
>
> Be well,
> Blueprint
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> *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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