Email Archive

Following Up on the Bioglutide Sample Janoshik Tested

Score 0.820 · Account tjphuhs@gmail.com · 5/14/2026, 8:58:14 PM

Following Up on the Bioglutide Sample Janoshik Tested from derekpruski@substack.com on 2026-05-15T00:58:14.000Z optional for serious research — it is the floor. The full write-up is worth your time. It walks through the NMR data, the mass spec data, and the broader mess around how Bioglutide is being marketed and sold despite no one being able to verify what it actually is. Read the full thread on X [ https://substack.com/redirect/f274a32f-65a4-4596-92b3-48130bbce16f?j=eyJ1IjoiNGl3b2U2In0.sVDxRt

Following Up on the Bioglutide Sample Janoshik Tested

Score 0.781 · Account tjphuhs@gmail.com · 5/14/2026, 8:58:14 PM

Following Up on the Bioglutide Sample Janoshik Tested from derekpruski@substack.com on 2026-05-15T00:58:14.000Z View this post on the web at https://derekpruski.substack.com/p/following-up-on-the-bioglutide-sample One of the members of the community sent this over and I want to walk you through it, because it’s one of the clearest examples I’ve seen of why independent identification testing matters in this space. If you caught my Janoshik podcast episode [ https://substack.com/redirect/fa47beae-

Following Up on the Bioglutide Sample Janoshik Tested

Score 0.709 · Account tjphuhs@gmail.com · 5/14/2026, 8:58:14 PM

Following Up on the Bioglutide Sample Janoshik Tested from derekpruski@substack.com on 2026-05-15T00:58:14.000Z the sample really was what the label claimed, the mass spec would show clear evidence of a peptide in that range, including the multiply charged envelope you would expect from a molecule that size. What Came Back The mass spec showed a parent mass of about 154 Daltons. Not 4,000. Not 5,000. One hundred and fifty four. That is not a peptide agonist. That is a small molecule. Roughly thi

Peptidology Just Upgraded Their Testing Standard and Their Discount

Score 0.649 · Account tjphuhs@gmail.com · 4/8/2026, 12:15:30 PM

Peptidology Just Upgraded Their Testing Standard and Their Discount from derekpruski@substack.com on 2026-04-08T16:15:30.000Z is a test a lot of vendors skip entirely. ICP-MS Heavy Metals ICP-MS (Inductively Coupled Plasma Mass Spectrometry) screens for toxic heavy metals: lead, arsenic, cadmium, mercury, and chromium. These can enter a product through the raw materials used in synthesis or through manufacturing equipment. You won’t taste or see them, and they won’t show up on a purity test — wh

Re: peptide_testing - Sample Submission

Score 0.648 · Account tjphuhs@gmail.com · 2/13/2026, 6:07:10 PM

Re: peptide_testing - Sample Submission from contact@bioregen.com on 2026-02-13T23:07:10.000Z Hi TJ, hank you for reaching out to BioRegen regarding testing services. We’re happy to assist with the testing of the sample. Please find the attached shipping form, which we kindly ask you to include with the samples you send. Our shipping address is listed at the bottom of the form for your convenience. You can also send your submission here: Sample Submission Link<https://reports.bioregen.com/sendsa

Fwd: Tesamorelin Degradation Data — We're Getting It After All | Peptide Crafters 3-Month Study | Month 1 Sneak Peek

Score 0.637 · Account tjphuhs@gmail.com · 3/19/2026, 8:53:16 AM

Fwd: Tesamorelin Degradation Data — We're Getting It After All | Peptide Crafters 3-Month Study | Month 1 Sneak Peek from tjphuhs@gmail.com on 2026-03-19T12:53:16.000Z ---------- Forwarded message ---------- From: Derek from Peptide Price <derekpruski@substack.com> Date: Mar 19, 2026 at 8:37 AM -0400 To: tjphuhs@gmail.com Subject: Tesamorelin Degradation Data — We're Getting It After All | Peptide Crafters 3-Month Study | Month 1 Sneak Peek > I know a lot of you were disappointed when our own de

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters

Score 0.629 · Account oc.tjphuhs@gmail.com · 3/18/2026, 9:54:30 AM

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters from tjphuhs@gmail.com on 2026-03-18T13:54:30.000Z I had the chance to meet the owner recently and we both landed on the same page — more real data in the hands of researchers is always the right call, regardless of any commercial relationship. They gave me permission to share early results from their latest round of Amazon BAC water testing. These COAs were just completed in March 2026 by Vanguard

Introducing Peptidology: Testing Taken To A New Level

Score 0.628 · Account tjphuhs@gmail.com · 3/24/2026, 11:15:15 AM

Introducing Peptidology: Testing Taken To A New Level from derekpruski@substack.com on 2026-03-24T15:15:15.000Z View this post on the web at https://derekpruski.substack.com/p/introducing-peptidology-testing-taken Without question the best-tested company I’ve come across in this space — and one of the first to do it at this level. Peptidology takes a different approach to the research space. Their goal is to do the maximum amount of testing possible to ensure their products are the highest quali

Re: Contact form submission

Score 0.628 · Account tjphuhs@gmail.com · 4/2/2026, 9:20:24 AM

Re: Contact form submission from admin@freedomdiagnostics.net on 2026-04-02T13:20:24.000Z Yes, we are able to test NAD and B12. Please let me know if you have any other questions. On Thu, Apr 2, 2026 at 8:49 AM <tjphuhs@gmail.com> wrote: > Can you test vitamins, ie NAD and B12 or is it just peptides? > On Feb 7, 2026 at 8:34 PM -0500, Freedom Diagnostics < > admin@freedomdiagnostics.net>, wrote: > > Thank you for reaching out. We would be happy to assist you. > > Our turnaround time is 24-48 hou

Fwd: Tesamorelin Degradation Baseline vs Month 1 | Room Temp vs Refrigerated | Peptide Crafters

Score 0.626 · Account tjphuhs@gmail.com · 3/19/2026, 3:17:25 PM

Fwd: Tesamorelin Degradation Baseline vs Month 1 | Room Temp vs Refrigerated | Peptide Crafters from tjphuhs@gmail.com on 2026-03-19T19:17:25.000Z what happens when you don’t. This study starts to answer that question with real numbers from a controlled comparison. > Study Setup > Same batch (PC-G2-TS10), three samples tested by Janoshik on February 16, 2026 to establish a starting point — think of this as the “before” snapshot. Two months of additional testing still to come. > Here’s how the ti

Fwd: Compound Tirzepatide & Semaglutide Updates!

Score 0.624 · Account tjphuhs@gmail.com · 3/17/2026, 5:51:48 PM

Fwd: Compound Tirzepatide & Semaglutide Updates! from tjphuhs@gmail.com on 2026-03-17T21:51:48.000Z exclusive DDC list explained Novo’s lab findings 302% dose shocker Catalent’s contamination mess Lilly’s B12 tirzepatide bombshell Is the molecule changing? New oral GLP-1 contender MASSIVE: Compound Tirzepatide and Semaglutide Updates! Dave Knapp GLP-1 Industry Insider Episode Do you trust compounded GLP-1s based on real-world experience, or do findings like the ones discussed today change your p

What Do You Do When Your First Vial Is Running Low?

Score 0.622 · Account tjphuhs@gmail.com · 3/15/2026, 10:50:16 AM

What Do You Do When Your First Vial Is Running Low? from derekpruski@substack.com on 2026-03-15T14:50:16.000Z cloudiness is a sign the peptide structure may be compromised. Gelling. Some lyophilized peptides are sensitive to environmental changes. Combining two solutions under different conditions can cause them to gel up or form aggregates — meaning the peptide is no longer properly dissolved and you can’t accurately dose it. None of those outcomes are what you want in a research setting where

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process

Score 0.620 · Account tjphuhs@gmail.com · 3/26/2026, 1:28:59 PM

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process from tjphuhs@gmail.com on 2026-03-26T17:28:59.000Z English: “Was the manufacturing process clean and controlled before it got here?” > USP 85 is the Bacterial Endotoxins Test (BET). It checks for endotoxins — toxic remnants left behind by certain gram-negative bacteria during the manufacturing process. Here’s the key thing most people miss: the bacteria themselves don’t have to be alive or present anymore. Even dead bact

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process

Score 0.620 · Account oc.tjphuhs@gmail.com · 3/26/2026, 1:28:59 PM

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process from tjphuhs@gmail.com on 2026-03-26T17:28:59.000Z English: “Was the manufacturing process clean and controlled before it got here?” > USP 85 is the Bacterial Endotoxins Test (BET). It checks for endotoxins — toxic remnants left behind by certain gram-negative bacteria during the manufacturing process. Here’s the key thing most people miss: the bacteria themselves don’t have to be alive or present anymore. Even dead bact

GW501516 (Cardarine) — Full Research Breakdown: Mechanisms, Cancer Data, and What the Human Trials Actually Show

Score 0.618 · Account tjphuhs@gmail.com · 3/26/2026, 10:30:40 AM

GW501516 (Cardarine) — Full Research Breakdown: Mechanisms, Cancer Data, and What the Human Trials Actually Show from derekpruski@substack.com on 2026-03-26T14:30:40.000Z possible bleeding risk at certain doses, though this was not observed in the human trials (Ali et al., 2009). Additionally, one animal study found cardarine may increase sphingomyelin synthesis, raising a potential atherosclerosis concern — again not replicated in human data (Bianchi et al., 2023). Practical Considerations The

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process

Score 0.618 · Account oc.tjphuhs@gmail.com · 3/26/2026, 1:28:59 PM

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process from tjphuhs@gmail.com on 2026-03-26T17:28:59.000Z ---------- Forwarded message ---------- From: Derek from Peptide Price <derekpruski@substack.com> Date: Mar 26, 2026 at 12:51 PM -0400 To: tjphuhs@gmail.com Subject: Past, Present, and Future: How to Verify a Clean Manufacturing Process > When you look at a certificate of analysis, you’re not looking at one thing. > ͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process

Score 0.618 · Account tjphuhs@gmail.com · 3/26/2026, 1:28:59 PM

Fwd: Past, Present, and Future: How to Verify a Clean Manufacturing Process from tjphuhs@gmail.com on 2026-03-26T17:28:59.000Z ---------- Forwarded message ---------- From: Derek from Peptide Price <derekpruski@substack.com> Date: Mar 26, 2026 at 12:51 PM -0400 To: tjphuhs@gmail.com Subject: Past, Present, and Future: How to Verify a Clean Manufacturing Process > When you look at a certificate of analysis, you’re not looking at one thing. > ͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏

Re:

Score 0.617 · Account tjphuhs@gmail.com · 2/11/2026, 12:00:03 PM

Re: from tjphuhs@gmail.com on 2026-02-11T17:00:03.000Z Here’s what I’m looking at. This is the COA from the supplier I am going with. Janoshik Analytical verify.janoshik.com It’s directly from Janoshik so them tampering with the COA is almost 0. Then I can also look at this which gives a rating to the suppliers. finnrick.com On Feb 11, 2026, at 10:25 AM, velvetlatte <sophiechloe404@gmail.com> wrote: No don’t worry you’re good. Thank you. I’ll keep researching and asking you questions as we go. O

Fwd: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria.

Score 0.616 · Account oc.tjphuhs@gmail.com · 5/3/2026, 2:45:39 PM

Fwd: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria. from tjphuhs@gmail.com on 2026-05-03T18:45:39.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: May 3, 2026 at 10:41 AM -0400 To: tjphuhs@gmail.com Subject: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria. > The body has always known something drug developers are still learning: shape matters. > ͏

Fwd: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria.

Score 0.616 · Account tjphuhs@gmail.com · 5/3/2026, 2:45:39 PM

Fwd: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria. from tjphuhs@gmail.com on 2026-05-03T18:45:39.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: May 3, 2026 at 10:41 AM -0400 To: tjphuhs@gmail.com Subject: A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria. > The body has always known something drug developers are still learning: shape matters. > ͏

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters

Score 0.616 · Account oc.tjphuhs@gmail.com · 3/18/2026, 9:54:30 AM

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters from tjphuhs@gmail.com on 2026-03-18T13:54:30.000Z in potency happens gradually. You won’t necessarily know until your results don’t make sense or your vial clouds up. Hospira BAC water has a long track record, known specs, and is what most legitimate research operations reach for by default. It’s not the only acceptable option, but it’s the standard for a reason. The cost difference between Hospir

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters

Score 0.616 · Account oc.tjphuhs@gmail.com · 3/18/2026, 9:54:30 AM

Fwd: BAC Water Amazon Testing — March 2026 | Only 2 of 11 Passed | Data Shared by Peptide Crafters from tjphuhs@gmail.com on 2026-03-18T13:54:30.000Z the peptide aggregates or degrades faster than expected, and they blame the peptide. The BAC water was the variable the whole time. The Data — 11 Amazon Samples Tested, March 2026 All testing performed by Vanguard Laboratory (A2LA accredited, ISO 17025). USP acceptable ranges: Benzyl Alcohol 0.72%–1.08% | pH 4.0–7.0 Parrox Reconstitution Solution —

Past, Present, and Future: How to Verify a Clean Manufacturing Process

Score 0.616 · Account tjphuhs@gmail.com · 3/26/2026, 12:51:37 PM

Past, Present, and Future: How to Verify a Clean Manufacturing Process from derekpruski@substack.com on 2026-03-26T16:51:37.000Z View this post on the web at https://derekpruski.substack.com/p/past-present-and-future-how-to-verify When you look at a certificate of analysis, you’re not looking at one thing. You’re looking at a snapshot across three different windows of time. Each test answers a completely different question — and once you understand that, a COA goes from a piece of paper with che

Two Vials of Tirzepatide Got Lost in the Mail for Two Years. Here's What the Data Showed.

Score 0.615 · Account tjphuhs@gmail.com · 5/9/2026, 7:49:04 AM

Two Vials of Tirzepatide Got Lost in the Mail for Two Years. Here's What the Data Showed. from derekpruski@substack.com on 2026-05-09T11:49:04.000Z View this post on the web at https://derekpruski.substack.com/p/two-vials-of-tirzepatide-got-lost A real-world stability test nobody planned for Peptide Crafters recently sent me a story I couldn’t pass up. Back in June 2024, they shipped an order containing two vials of tirzepatide. The package never made it. UPS lost it somewhere in the system, and

New Testing Standards at Southern Aminos

Score 0.614 · Account tjphuhs@gmail.com · 3/30/2026, 3:53:11 PM

New Testing Standards at Southern Aminos from derekpruski@substack.com on 2026-03-30T19:53:11.000Z View this post on the web at https://derekpruski.substack.com/p/new-testing-standards-at-southern Most vendors send one vial to a lab and call it a day. Southern Aminos is now running full testing across 10 vials per batch — and closing in on a 6.5/7 score on the PeptidePrice.store testing standard. That’s not a small thing. Here’s exactly what that means for your research. What Does “Full Peptide