Email Archive

Open Tab: Esther Perel

Score 0.766 · Account tjphuhs@gmail.com · 5/12/2026, 12:04:35 PM

Open Tab: Esther Perel from on+open-tab@substack.com on 2026-05-12T16:04:35.000Z View this post on the web at https://on.substack.com/p/open-tab-esther-perel The psychotherapy room is, by design, one of the most private spaces in human life, but Esther Perel has devoted much of her career to opening the door. Addressing relationships, cross-cultural psychology, and the contours of belonging, she brought therapeutic ideas out into the world through a body of work that spans talks, books, and her

Open Tab: Esther Perel

Score 0.760 · Account tjphuhs@gmail.com · 5/12/2026, 12:04:35 PM

Open Tab: Esther Perel from on+open-tab@substack.com on 2026-05-12T16:04:35.000Z then depending on whichever way they learn, I say, and what was it? What’s one thing that has actually been useful for you? And then I can handle it. Then I feel like there is substance here. FOOTNOTES Temple Bar [ https://substack.com/redirect/0b74a544-6e36-4e0f-82b7-5c22119c1757?j=eyJ1IjoiNGl3b2U2In0.sVDxRtmZ85v8kfdamY0krRXGMy3p768BWtuZifRB-Zs ], 332 Hudson St., New York—SoHo fixture with a long bar and low lighti

Open Tab: Esther Perel

Score 0.711 · Account tjphuhs@gmail.com · 5/12/2026, 12:04:35 PM

Open Tab: Esther Perel from on+open-tab@substack.com on 2026-05-12T16:04:35.000Z Esther: There are so many ways to answer this. I have never worked for anyone. I’ve worked for clinics, I’ve worked in hospitals, but I’ve never been a full-time employee somewhere. And I always said, I can tolerate the lack of security better than I can tolerate the lack of freedom. This was the life of the therapist. You do it all by yourself. And that’s part of why at some point I feel like I want more, I want so

Open Tab: Esther Perel

Score 0.710 · Account tjphuhs@gmail.com · 5/12/2026, 12:04:35 PM

Open Tab: Esther Perel from on+open-tab@substack.com on 2026-05-12T16:04:35.000Z ask them, what did the tarot reader say? Bring me the astrology chart. Let’s read it together. Maybe they see something you don’t see. Don’t be so insecure. So now I say to my students, do the same with AI. Don’t just have them tell you. Ask them, what did ChatGPT say? Bring it to me. Open your phone. Let’s read it together. And make it useful for the work you’re doing. You want to learn to say something? Tell the c

Open Tab: Esther Perel

Score 0.703 · Account tjphuhs@gmail.com · 5/12/2026, 12:04:35 PM

Open Tab: Esther Perel from on+open-tab@substack.com on 2026-05-12T16:04:35.000Z what drives me. I like to matter, because if I matter, I can’t be erased. Hanne: You said earlier that you never wanted to build a media business, but you have. What makes you different as a leader? Esther: Because I’ve always been self-employed, I have gravitated towards people who are like that too: experts in their own field. When they tell me what to do, I listen and I do it, because I think they understand this

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.544 · Account tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > • > News-Medical coverage: “New quintuple agonist shows promise for treating obesity and type 2 diabetes.” September 21, 2025. news-medical.net > • > Andreassen KV, et al. Research on Dual Amylin and Calcitonin Receptor Agonists (DACRAs, KBP-042, KBP-089) — various publications > • > Eli Lilly pipeline page (no quintuple currently listed): lilly.com/science/research-de

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.544 · Account oc.tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > • > News-Medical coverage: “New quintuple agonist shows promise for treating obesity and type 2 diabetes.” September 21, 2025. news-medical.net > • > Andreassen KV, et al. Research on Dual Amylin and Calcitonin Receptor Agonists (DACRAs, KBP-042, KBP-089) — various publications > • > Eli Lilly pipeline page (no quintuple currently listed): lilly.com/science/research-de

Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.544 · Account tjphuhs@gmail.com · 4/24/2026, 9:05:46 AM

Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z still mouse data Mouse-to-market is typically 8-12 years Retatrutide is what’s actually arriving soon Eloralintide is what’s actually advancing through Phase 3 for amylin The quintuple, if real, is a late-decade story The most important thing to do right now is stay curious and stay patient. Let the science play out. Don’t build expectations around compounds that haven

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.543 · Account tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z ---------- Forwarded message ---------- From: Derek from Research Radar <derekpruski@substack.com> Date: Apr 24, 2026 at 9:10 AM -0400 To: tjphuhs@gmail.com Subject: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine > Let’s talk about one of the biggest stories currently brewing in the obesity and metabolic disease space — Eli Lilly’s rumored quintup

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.543 · Account oc.tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z ---------- Forwarded message ---------- From: Derek from Research Radar <derekpruski@substack.com> Date: Apr 24, 2026 at 9:10 AM -0400 To: tjphuhs@gmail.com Subject: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine > Let’s talk about one of the biggest stories currently brewing in the obesity and metabolic disease space — Eli Lilly’s rumored quintup

Fwd: Compound Tirzepatide & Semaglutide Updates!

Score 0.536 · Account tjphuhs@gmail.com · 3/17/2026, 5:51:48 PM

Fwd: Compound Tirzepatide & Semaglutide Updates! from tjphuhs@gmail.com on 2026-03-17T21:51:48.000Z exclusive DDC list explained Novo’s lab findings 302% dose shocker Catalent’s contamination mess Lilly’s B12 tirzepatide bombshell Is the molecule changing? New oral GLP-1 contender MASSIVE: Compound Tirzepatide and Semaglutide Updates! Dave Knapp GLP-1 Industry Insider Episode Do you trust compounded GLP-1s based on real-world experience, or do findings like the ones discussed today change your p

Martin Short Breaks Silence On Daughter Katherine's Death: 'A Nightmare'

Score 0.531 · Account tjphuhs@gmail.com · 5/11/2026, 3:52:18 PM

Martin Short Breaks Silence On Daughter Katherine's Death: 'A Nightmare' from tampabaysmix@e.iheart.com on 2026-05-11T19:52:18.000Z iHeart Daily 96 Plus, Rita Wilson opens up about new album inspired by breast cancer battle&zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwnj; &zwn

Re: Paper Access [260213-004644]

Score 0.531 · Account tjphuhs@gmail.com · 2/12/2026, 4:54:03 PM

Re: Paper Access [260213-004644] from patientaccess@elsevier.com on 2026-02-12T21:54:03.000Z FROM: Administrator DATE: 12/02/2026 09.54 PM Dear TJ Bourdeau, Thank you for contacting Elsevier. We prioritize providing high-quality, up-to-date information swiftly. We aim to deliver requested articles within 48 hours. To help us process your request efficiently, please include in your email: •Article title and author(s) •Publication date •URL •The statement: “I confirm I am a patient or non-professi

Re: Paper Access [260213-004608]

Score 0.530 · Account tjphuhs@gmail.com · 2/12/2026, 4:50:20 PM

Re: Paper Access [260213-004608] from patientaccess@elsevier.com on 2026-02-12T21:50:20.000Z FROM: Administrator DATE: 12/02/2026 09.50 PM Dear TJ Bourdeau, Thank you for contacting Elsevier. We prioritize providing high-quality, up-to-date information swiftly. We aim to deliver requested articles within 48 hours. To help us process your request efficiently, please include in your email: •Article title and author(s) •Publication date •URL •The statement: “I confirm I am a patient or non-professi

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention

Score 0.526 · Account oc.tjphuhs@gmail.com · 5/1/2026, 9:18:21 AM

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention from tjphuhs@gmail.com on 2026-05-01T13:18:21.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: May 1, 2026 at 7:34 AM -0400 To: tjphuhs@gmail.com Subject: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention > Anecdotes are slowly becoming science > ͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention

Score 0.526 · Account tjphuhs@gmail.com · 5/1/2026, 9:18:21 AM

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention from tjphuhs@gmail.com on 2026-05-01T13:18:21.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: May 1, 2026 at 7:34 AM -0400 To: tjphuhs@gmail.com Subject: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention > Anecdotes are slowly becoming science > ͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏ ­͏

(no subject)

Score 0.523 · Account tjphuhs@gmail.com · 2/18/2026, 10:55:28 AM

(no subject) from sophiechloe404@gmail.com on 2026-02-18T15:55:28.000Z Did the Reta get to you yet

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention

Score 0.523 · Account oc.tjphuhs@gmail.com · 5/1/2026, 9:18:21 AM

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention from tjphuhs@gmail.com on 2026-05-01T13:18:21.000Z study population that was predominantly White. The researchers themselves are careful to say that larger, more diverse studies are needed before anyone should consider using this drug off-label for AUD. > Upgrade to paid > This is just the beginning. Eli Lilly has a dual GLP-1/GIP co-agonist called brenipatide that is being looked at for a whole host of nueralogical d

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention

Score 0.523 · Account tjphuhs@gmail.com · 5/1/2026, 9:18:21 AM

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention from tjphuhs@gmail.com on 2026-05-01T13:18:21.000Z study population that was predominantly White. The researchers themselves are careful to say that larger, more diverse studies are needed before anyone should consider using this drug off-label for AUD. > Upgrade to paid > This is just the beginning. Eli Lilly has a dual GLP-1/GIP co-agonist called brenipatide that is being looked at for a whole host of nueralogical d

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.522 · Account oc.tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > Upgrade to paid > I want to walk through what’s actually going on here, because there’s real, exciting science behind this AND there’s a lot of social media buzz that’s getting mashed together. The mechanism is fascinating, the trajectory of the field is remarkable, and calcitonin in particular could solve problems nobody has solved yet. > This post is going to cover w

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.522 · Account tjphuhs@gmail.com · 4/24/2026, 9:42:34 AM

Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > Upgrade to paid > I want to walk through what’s actually going on here, because there’s real, exciting science behind this AND there’s a lot of social media buzz that’s getting mashed together. The mechanism is fascinating, the trajectory of the field is remarkable, and calcitonin in particular could solve problems nobody has solved yet. > This post is going to cover w

Sunday Scoop: This one's for her

Score 0.521 · Account tjphuhs@gmail.com · 5/10/2026, 9:00:22 AM

Sunday Scoop: This one's for her from no-reply@truenutrition.com on 2026-05-10T13:00:22.000Z FREE GROUND SHIPPING ON ORDERS $99 & UP* https://www.truenutrition.com https://www.truenutrition.com [Shop](https://www.truenutrition.com) [About](https://truenutrition.com/pages/about-us) [Community](https://truenutrition.com/pages/community) https://truenutrition.com/collections/the-lab https://truenutrition.com/blogs/news/formulated-for-her-female-focused-formulas https://truenutrition.com/blogs/news/

Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine

Score 0.520 · Account tjphuhs@gmail.com · 4/24/2026, 9:05:46 AM

Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z single dose and push efficacy into territory that previously only bariatric surgery could reach. ═══════════════════════════════ THE FIVE RECEPTORS AND WHY EACH MATTERS The rumored Lilly quintuple reportedly targets GLP-1, GIP, glucagon, amylin, and calcitonin. Let’s break down what each one actually does. GLP-1 (Glucagon-Like Peptide-1) This is the backbone of every m

5-Bullet Friday — Art Thieves, At-Home Brain Stimulation, Dwarkesh’s Origin Story, and Tide Shifts

Score 0.520 · Account tjphuhs@gmail.com · 5/8/2026, 7:51:46 PM

5-Bullet Friday — Art Thieves, At-Home Brain Stimulation, Dwarkesh’s Origin Story, and Tide Shifts from tim@fourhourbody.com on 2026-05-08T23:51:46.000Z “The Lunar Society,” his original name for the podcast, from his dorm room at the University of Texas at Austin in 2020, during the early months of the Covid pandemic, when he was 19. He was taking online classes, bored, and thirsty for intellectual engagement. So he did what any normal college sophomore might do and cold-emailed Bryan Caplan, a

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention

Score 0.518 · Account oc.tjphuhs@gmail.com · 5/1/2026, 9:18:21 AM

Fwd: Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention from tjphuhs@gmail.com on 2026-05-01T13:18:21.000Z wanted it badly enough, you’d find your way out eventually. Sound familiar? > If you’ve lived inside the obesity fight, you know this cycle all too well. The same cycle of white knuckle effort and utter disappointment. The same medical shrug. The same story that put the weight of a biological condition squarely on the shoulders of the person carrying it. Two different