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Semantic Search: New Reagent Release: Melatonin + GABA Solution
New Reagent Release: Melatonin + GABA Solution
Score 0.895
· Account tjphuhs@gmail.com
· 3/19/2026, 10:00:37 AM
New Reagent Release: Melatonin + GABA Solution from happy@happypeptides.com on 2026-03-19T14:00:37.000Z A new addition to the Reagents & Solutions collection. This email was sent to you as HTML-only. To view it, please visit: https://wfg.soundestlink.com/ce/v/68a8a1cb95c4ac11474be077/69bbc8f6261b51940bbbb621 ************************** Make sure you keep getting our latest offers and add happy@happypeptides.com to your address book. Unsubscribe https://wfg.soundestlink.com/contactsPreferences/v2/
Bryan Johnson’s adaptogen protocol
Score 0.652
· Account tjphuhs@gmail.com
· 3/20/2026, 4:02:31 PM
Bryan Johnson’s adaptogen protocol from hello@bryanjohnson.com on 2026-03-20T20:02:31.000Z [Ashwagandha + Rhodiola support stress response, cognitive function and a balanced mood](https://blueprint.bryanjohnson.com/collections/ashwagandha-rhodiola) How to get ashwagandha and rhodiola You can supplement these adaptogens. We’ve combined ashwagandha and rhodiola into 1 daily capsule. In 1 capsule, you’ll get: - + 120mg of ashwagandha + 300mg of rhodiola Combining ashwagandha and rhodiola means you
Fwd: Compound Tirzepatide & Semaglutide Updates!
Score 0.643
· Account tjphuhs@gmail.com
· 3/17/2026, 5:51:48 PM
Fwd: Compound Tirzepatide & Semaglutide Updates! from tjphuhs@gmail.com on 2026-03-17T21:51:48.000Z exclusive DDC list explained Novo’s lab findings 302% dose shocker Catalent’s contamination mess Lilly’s B12 tirzepatide bombshell Is the molecule changing? New oral GLP-1 contender MASSIVE: Compound Tirzepatide and Semaglutide Updates! Dave Knapp GLP-1 Industry Insider Episode Do you trust compounded GLP-1s based on real-world experience, or do findings like the ones discussed today change your p
Peptira Just Dropped 3 New Amino Blends — And None of Them Contain B12
Score 0.640
· Account tjphuhs@gmail.com
· 3/30/2026, 4:25:58 PM
Peptira Just Dropped 3 New Amino Blends — And None of Them Contain B12 from derekpruski@substack.com on 2026-03-30T20:25:58.000Z processes NAD+ is a coenzyme required for energy production in every cell in the body. Research interest around NAD+ has expanded significantly in recent years, particularly around its decline with age and the downstream effects on cellular function and longevity B6 and methionine are studied as methylation cofactors — methylation being the process the body uses to reg
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.639
· Account tjphuhs@gmail.com
· 4/24/2026, 9:05:46 AM
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z still mouse data Mouse-to-market is typically 8-12 years Retatrutide is what’s actually arriving soon Eloralintide is what’s actually advancing through Phase 3 for amylin The quintuple, if real, is a late-decade story The most important thing to do right now is stay curious and stay patient. Let the science play out. Don’t build expectations around compounds that haven
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.638
· Account tjphuhs@gmail.com
· 4/24/2026, 9:05:46 AM
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z single dose and push efficacy into territory that previously only bariatric surgery could reach. ═══════════════════════════════ THE FIVE RECEPTORS AND WHY EACH MATTERS The rumored Lilly quintuple reportedly targets GLP-1, GIP, glucagon, amylin, and calcitonin. Let’s break down what each one actually does. GLP-1 (Glucagon-Like Peptide-1) This is the backbone of every m
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.636
· Account tjphuhs@gmail.com
· 4/24/2026, 9:05:46 AM
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z control (the tirzepatide backbone) Adding glucagon brings fat-burning and energy expenditure (the retatrutide upgrade) Adding amylin brings extended satiety and slowed gastric emptying from a different pathway Adding calcitonin brings longer-duration satiety, insulin sensitivity, and bone/joint protection On paper, you’d be combining the best of everything that’s alrea
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.631
· Account oc.tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z and GIP give core appetite and blood sugar control (the tirzepatide backbone) > • > Adding glucagon brings fat-burning and energy expenditure (the retatrutide upgrade) > • > Adding amylin brings extended satiety and slowed gastric emptying from a different pathway > • > Adding calcitonin brings longer-duration satiety, insulin sensitivity, and bone/joint protection > > O
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.631
· Account tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z and GIP give core appetite and blood sugar control (the tirzepatide backbone) > • > Adding glucagon brings fat-burning and energy expenditure (the retatrutide upgrade) > • > Adding amylin brings extended satiety and slowed gastric emptying from a different pathway > • > Adding calcitonin brings longer-duration satiety, insulin sensitivity, and bone/joint protection > > O
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.630
· Account oc.tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z PPAR part is only released inside cells that express GLP-1 or GIP receptors, so it’s targeted rather than systemic. > Mouse models showed it outperformed GLP-1/GIP co-agonism alone on both weight and glucose control. > This is academic preclinical work — not owned by Lilly, not in human trials — but it demonstrates that pushing past three receptor targets is a legitimate
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.630
· Account tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z PPAR part is only released inside cells that express GLP-1 or GIP receptors, so it’s targeted rather than systemic. > Mouse models showed it outperformed GLP-1/GIP co-agonism alone on both weight and glucose control. > This is academic preclinical work — not owned by Lilly, not in human trials — but it demonstrates that pushing past three receptor targets is a legitimate
CLOMID - The OG PCT Solution
Score 0.630
· Account tjphuhs@gmail.com
· 5/11/2026, 12:30:12 PM
CLOMID - The OG PCT Solution from hello@pctz.news on 2026-05-11T16:30:12.000Z
Fwd: When Ozempic stops working (and what 10% of users already know)
Score 0.629
· Account tjphuhs@gmail.com
· 3/17/2026, 2:05:41 PM
Fwd: When Ozempic stops working (and what 10% of users already know) from tjphuhs@gmail.com on 2026-03-17T18:05:41.000Z Rate Problem Retatrutide is Eli Lilly's triple agonist (GIP/GLP-1/glucagon). Early results: up to 24.2% weight loss at 48 weeks per the NEJM Phase 2 trial. But buried in the data: dose-dependent increases in heart rate peaking at 24 weeks. The glucagon receptor component is the likely culprit. At the 12mg dose, heart rate elevations were clinically notable. Users report resting
GLP-1 Mental Flatness & Anhedonia — Peptides Worth Researching
Score 0.628
· Account tjphuhs@gmail.com
· 4/4/2026, 8:24:03 PM
GLP-1 Mental Flatness & Anhedonia — Peptides Worth Researching from derekpruski@substack.com on 2026-04-05T00:24:03.000Z you want to start a task, finish a project, or feel rewarded after doing something. GLP-1 compounds can dial down dopamine activity in these areas — not dramatically, but enough that some RS subjects notice a consistent low-grade flatness that doesn’t go away on its own. The same mechanism making the compounds so effective at reducing compulsive eating can also reduce the brai
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.627
· Account tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > • > News-Medical coverage: “New quintuple agonist shows promise for treating obesity and type 2 diabetes.” September 21, 2025. news-medical.net > • > Andreassen KV, et al. Research on Dual Amylin and Calcitonin Receptor Agonists (DACRAs, KBP-042, KBP-089) — various publications > • > Eli Lilly pipeline page (no quintuple currently listed): lilly.com/science/research-de
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.627
· Account oc.tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z > • > News-Medical coverage: “New quintuple agonist shows promise for treating obesity and type 2 diabetes.” September 21, 2025. news-medical.net > • > Andreassen KV, et al. Research on Dual Amylin and Calcitonin Receptor Agonists (DACRAs, KBP-042, KBP-089) — various publications > • > Eli Lilly pipeline page (no quintuple currently listed): lilly.com/science/research-de
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.626
· Account tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z actually does. > GLP-1 (Glucagon-Like Peptide-1) > This is the backbone of every modern weight loss drug, from semaglutide forward. GLP-1 stimulates insulin release when blood sugar is high, suppresses glucagon (preventing unnecessary sugar release from the liver), and slows gastric emptying so you feel full longer. It also acts directly on the brain’s appetite centers i
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.626
· Account oc.tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z actually does. > GLP-1 (Glucagon-Like Peptide-1) > This is the backbone of every modern weight loss drug, from semaglutide forward. GLP-1 stimulates insulin release when blood sugar is high, suppresses glucagon (preventing unnecessary sugar release from the liver), and slows gastric emptying so you feel full longer. It also acts directly on the brain’s appetite centers i
Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For
Score 0.626
· Account tjphuhs@gmail.com
· 3/25/2026, 9:43:26 AM
Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For from derekpruski@substack.com on 2026-03-25T13:43:26.000Z View this post on the web at https://derekpruski.substack.com/p/modified-aminos-new-products-including Modified Aminos just launched a full lineup of new products, and the one I was most excited about — and that a lot of you have been requesting — is the KPV nasal spray at 10mg per bottle. I took the community feedback seriously. A lot of you wanted higher
Fwd: Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For
Score 0.626
· Account tjphuhs@gmail.com
· 3/25/2026, 9:47:24 AM
Fwd: Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For from tjphuhs@gmail.com on 2026-03-25T13:47:24.000Z Link: https://modifiedaminos.shop/product/semax-spray-40mg-per-bottle/?ref=derek > > Semax/Selank Spray — 10mg/10mg (new size) > > • > Single: $77.99 > • > Two-Pack: $149.99 > • > Trio: $219.99 > • > Link: https://modifiedaminos.shop/product/semax-selank-spray-20/?ref=derek > > TB-500 Spray — 30mg > > • > Single: $138.99 > • > Two-Pack: $269.99 > • > Trio: $
Fwd: Compound Tirzepatide & Semaglutide Updates!
Score 0.625
· Account tjphuhs@gmail.com
· 3/17/2026, 5:51:48 PM
Fwd: Compound Tirzepatide & Semaglutide Updates! from tjphuhs@gmail.com on 2026-03-17T21:51:48.000Z TJ Begin forwarded message: From: Dave Knapp from On The Pen <onthepen@substack.com> Date: March 17, 2026 at 4:03:57 PM EDT To: tjphuhs@gmail.com Subject: Compound Tirzepatide & Semaglutide Updates! Reply-To: Dave Knapp from On The Pen <reply+35w1tf&4iwoe6&&9985d0eabdad8d3ee001e8d18022b7e3ec1f9e03481cf6e0f518cbf32ac3e62e@mg1.substack.com> Compound Tirzepatide & Semaglutide Updates! Happy Spring Br
Fwd: Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For
Score 0.625
· Account tjphuhs@gmail.com
· 3/25/2026, 9:47:24 AM
Fwd: Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For from tjphuhs@gmail.com on 2026-03-25T13:47:24.000Z ---------- Forwarded message ---------- From: Derek from Peptide Price <derekpruski@substack.com> Date: Mar 25, 2026 at 9:43 AM -0400 To: tjphuhs@gmail.com Subject: Modified Aminos New Products — Including the KPV Nasal Spray You’ve Been Asking For > Modified Aminos just launched a full lineup of new products, and the one I was most excited about — and that
New Product: Mitochondrial B12
Score 0.625
· Account tjphuhs@gmail.com
· 4/9/2026, 7:06:17 AM
New Product: Mitochondrial B12 from support@simplepeptide.com on 2026-04-09T11:06:17.000Z A closer look at its role in mitochondrial and metabolic research This email was sent to you as HTML-only. To view it, please visit: https://ptv.soundestlink.com/ce/v/6864b11c9f318c74accf8c6b/69d636772ee3c1bbc4ee1af6 ************************** Make sure you keep getting our latest offers and add support@simplepeptide.com to your address book. Unsubscribe https://ptv.soundestlink.com/contactsPreferences/v2/u
NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend
Score 0.624
· Account tjphuhs@gmail.com
· 3/27/2026, 4:31:44 PM
NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend from derekpruski@substack.com on 2026-03-27T20:31:44.000Z Vial contents: 100mg NAD+ / 10mg MOTS-c / 10mg 5-Amino-1MQ Add 3ml of bacteriostatic water to the vial. Store reconstituted vial refrigerated. Each 30-unit (0.3ml) research dose yields 1mg NAD+, 0.1mg MOTS-c, and 0.1mg 5-Amino-1MQ — a 10-1-1 ratio that keeps all three compounds proportional throughout the vial. Compound Summary NAD+ is the direct energy substrate — it supplies what mito
The Next Wave of GLP-1s Is Coming
Score 0.623
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z Happy Tuesday! There are two peptides quietly making waves in the clinical space that will demand all of our attention over the next 24 months. They don't work like semaglutide, they don't work like tirzepatide, and the clinical data is turning heads. I just dropped a brand new video breaking down survodutide and mazdutide. Survodutide & Mazdutide | The GLP-1/Glucagon Duo That Could Rival Reta: