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Semantic Search: GLP-1 vs GLP-2 vs GLP-3
GLP-1 vs GLP-2 vs GLP-3
Score 0.798
· Account tjphuhs@gmail.com
· 5/14/2026, 9:00:21 AM
GLP-1 vs GLP-2 vs GLP-3 from happy@happypeptides.com on 2026-05-14T13:00:21.000Z A simple comparison of the three. This email was sent to you as HTML-only. To view it, please visit: https://wfg.soundestlink.com/ce/v/68a8a1cb95c4ac11474be077/6a04d2931ac007f30c9a1cd2 ************************** Make sure you keep getting our latest offers and add happy@happypeptides.com to your address book. Unsubscribe https://wfg.soundestlink.com/contactsPreferences/v2/unsubscribe/?b=68a8a136cfa3b70cffc67e5f&c=68
The Next Wave of GLP-1s Is Coming
Score 0.647
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z the GLP-1 world. They're not retatrutide. But they're not far off. And they fill important gaps that tirzepatide and semaglutide can't address. Whether you use them as a primary GLP-1, an alternative for people who don't tolerate retatrutide well, or a rotation compound to maintain receptor sensitivity, I think they're worth researching. Remember to check out the video for the full breakdown. A
Phases 1 and 2
Score 0.639
· Account tjphuhs@gmail.com
· 2/23/2026, 11:07:28 PM
Phases 1 and 2 from noralouj@gmail.com on 2026-02-24T04:07:28.000Z gluteresetphase1.pdf <https://drive.google.com/file/d/1ZfBqX5wRap7xu_deKKNWB1HOrxrEUlcp/view?usp=drive_web> gluteresetphase2.pdf <https://drive.google.com/file/d/1Ajgl0Fe7pyeKgUZvvKmHtiY3ig5QwhZB/view?usp=drive_web>
The Next Wave of GLP-1s Is Coming
Score 0.635
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z fat and energy expenditure benefits that GIP agonism simply does not. Retatrutide is still king on paper. It hits all three receptors and delivers the most weight loss. But survodutide and mazdutide are not far behind. And for people who need an alternative, or who want to cycle compounds to maintain receptor sensitivity, these fill a real gap. ——————————————————————————— **They're Not the Same
The Next Wave of GLP-1s Is Coming
Score 0.632
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z approved doses in China are 4 mg and 6 mg per week. The titration protocol starts at 2 mg, then moves to 4 mg, then to 6 mg, with about four weeks between each step. The 9 mg dose is the highest studied in China's GLORY-2 trial. The US is evaluating doses up to 16 mg. Survodutide is also once weekly. Phase 3 target doses are 3.6 mg and 6.0 mg. Phase 2 used aggressive bi-weekly escalation and it
😱 GLP-3 (RETA) vs MOTS-C 😱
Score 0.627
· Account tjphuhs@gmail.com
· 2/11/2026, 10:30:15 AM
😱 GLP-3 (RETA) vs MOTS-C 😱 from info@somachems.com on 2026-02-11T15:30:15.000Z Take your metabolic research to the next level This email was sent to you as HTML-only. To view it, please visit: https://qfq.soundestlink.com/ce/v/68a3ebb905e51bffe64c8eaf/698c2a47dd9732c63e198315 ************************** Make sure you keep getting our latest offers and add info@somachems.com to your address book. Unsubscribe https://qfq.soundestlink.com/contactsPreferences/v2/unsubscribe/?b=686794eb7d5d9b4678a0b
Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In
Score 0.623
· Account oc.tjphuhs@gmail.com
· 4/7/2026, 1:00:10 PM
Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: Mar 28, 2026 at 1:38 PM -0400 To: tjphuhs@gmail.com Subject: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In > If you’re currently on a GLP-1, or if you’ve been on one long enough to feel your body experience massive changes, you already understand why this conversatio
Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In
Score 0.623
· Account tjphuhs@gmail.com
· 4/7/2026, 1:00:10 PM
Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: Mar 28, 2026 at 1:38 PM -0400 To: tjphuhs@gmail.com Subject: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In > If you’re currently on a GLP-1, or if you’ve been on one long enough to feel your body experience massive changes, you already understand why this conversatio
Non-GLP Fat Loss Compounds Ranked
Score 0.615
· Account tjphuhs@gmail.com
· 5/5/2026, 6:03:45 PM
Non-GLP Fat Loss Compounds Ranked from huntershealthhacks@mail.beehiiv.com on 2026-05-05T22:03:45.000Z Happy Tuesday! Most folks would agree that the GLPs are the kings of fat loss, with retatrutide holding the title belt. But what if GLPs are not on the table for you? What if you are cycling off? What if you want to stack other compounds so you don’t have to crank your GLP dose into the stratosphere? I just dropped a brand-new video and podcast episode where I rank **20 non-GLP-1 fat-loss**** c
Fwd: Waking Up at 2–3am While Researching a GLP-1? Read This.
Score 0.612
· Account tjphuhs@gmail.com
· 3/18/2026, 4:18:18 PM
Fwd: Waking Up at 2–3am While Researching a GLP-1? Read This. from tjphuhs@gmail.com on 2026-03-18T20:18:18.000Z overthink it — just make sure there’s enough fuel in the tank before lights out. > As always, this is for research purposes only. All compounds are research use only, not for human consumption. > Drop any questions below — happy to help you troubleshoot. > Upgrade to paid > You're currently a free subscriber to Peptide Price. For the full experience, upgrade your subscription. > Upgra
GLP-1 Mental Flatness & Anhedonia — Peptides Worth Researching
Score 0.599
· Account tjphuhs@gmail.com
· 4/4/2026, 8:24:03 PM
GLP-1 Mental Flatness & Anhedonia — Peptides Worth Researching from derekpruski@substack.com on 2026-04-05T00:24:03.000Z and produce mood-adjacent effects through its central mechanism. Dosing being explored runs 500 mcg – 2 mg per research administration, administered 1–2 hours before the relevant observation window. Most community research starts at the lower end — 500 mcg to 1 mg — to assess tolerance before titrating up. Frequency is kept to a maximum of 2–3x per week to avoid the receptors
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption?
Score 0.598
· Account oc.tjphuhs@gmail.com
· 4/25/2026, 9:07:43 PM
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption? from tjphuhs@gmail.com on 2026-04-26T01:07:43.000Z wrong on GLP-1 protocols isn’t usually absorption — it’s the dramatic reduction in intake that gets ignored because the appetite suppression is doing its job. > Pay attention to what you’re putting in. Slowed gastric emptying is doing interesting things to the timing, but it can’t manufacture nutrition out of food that isn’t there. > This article is for research and
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption?
Score 0.598
· Account tjphuhs@gmail.com
· 4/25/2026, 9:07:43 PM
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption? from tjphuhs@gmail.com on 2026-04-26T01:07:43.000Z wrong on GLP-1 protocols isn’t usually absorption — it’s the dramatic reduction in intake that gets ignored because the appetite suppression is doing its job. > Pay attention to what you’re putting in. Slowed gastric emptying is doing interesting things to the timing, but it can’t manufacture nutrition out of food that isn’t there. > This article is for research and
GLP-1 Access State of the Union
Score 0.597
· Account tjphuhs@gmail.com
· 4/7/2026, 4:01:22 PM
GLP-1 Access State of the Union from onthepen@substack.com on 2026-04-07T20:01:22.000Z View this post on the web at https://onthepen.substack.com/p/glp-1-access-state-of-the-union If you just look at the headlines, things look great for access to GLP-1 medications but for some of those already using these medications things are changing and getting tighter. Listen in as Dave breaks down the news of the week and puts it all in context. Watch or listen to this week’s podcast on Spotify! If you pre
GLP-1s vs. Fertility
Score 0.596
· Account tjphuhs@gmail.com
· 5/4/2026, 6:05:41 PM
GLP-1s vs. Fertility from huntershealthhacks@mail.beehiiv.com on 2026-05-04T22:05:41.000Z all. For couples whose fertility is being dragged down by metabolic dysfunction, GLP-1s are the most promising pharmacological lever I've seen in a decade. The female data on PCOS pregnancy rates is the strongest signal in the whole literature. The male data is catching up. The next 24 months of trial data will tell us a lot. I'll keep you posted on what we learn, on our journey, and on the science. GLP-1s
Fwd: How Long Does It Actually Take To Resensitize Your GLP-1 Receptors?
Score 0.595
· Account oc.tjphuhs@gmail.com
· 3/15/2026, 2:45:56 PM
Fwd: How Long Does It Actually Take To Resensitize Your GLP-1 Receptors? from tjphuhs@gmail.com on 2026-03-15T18:45:56.000Z Week > Week 0 - Administration stops > Plasma levels begin their slow decline. Receptors are getting their first break from continuous stimulation, but clearance is far from complete and meaningful resensitization hasn’t started. > Weeks 1-2 > Significant compound is still circulating. Appetite will likely begin creeping back up and gastric emptying will start accelerating
The Next Wave of GLP-1s Is Coming
Score 0.594
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z Happy Tuesday! There are two peptides quietly making waves in the clinical space that will demand all of our attention over the next 24 months. They don't work like semaglutide, they don't work like tirzepatide, and the clinical data is turning heads. I just dropped a brand new video breaking down survodutide and mazdutide. Survodutide & Mazdutide | The GLP-1/Glucagon Duo That Could Rival Reta:
Fwd: Nobody Lost 7 Pounds of Fat in Their First Week on a GLP-1. Let's Talk About Why.
Score 0.594
· Account oc.tjphuhs@gmail.com
· 3/16/2026, 10:27:30 AM
Fwd: Nobody Lost 7 Pounds of Fat in Their First Week on a GLP-1. Let's Talk About Why. from tjphuhs@gmail.com on 2026-03-16T14:27:30.000Z larger. What Actually Happens When Someone Starts a GLP-1 GLP-1 compounds work by suppressing appetite, slowing gastric emptying, and improving insulin sensitivity. The appetite suppression in particular is real and meaningful — most people naturally and significantly reduce how much food they’re eating, often without even trying. Here’s where it gets interest
Fwd: Nobody Lost 7 Pounds of Fat in Their First Week on a GLP-1. Let's Talk About Why.
Score 0.594
· Account tjphuhs@gmail.com
· 3/16/2026, 10:27:30 AM
Fwd: Nobody Lost 7 Pounds of Fat in Their First Week on a GLP-1. Let's Talk About Why. from tjphuhs@gmail.com on 2026-03-16T14:27:30.000Z larger. What Actually Happens When Someone Starts a GLP-1 GLP-1 compounds work by suppressing appetite, slowing gastric emptying, and improving insulin sensitivity. The appetite suppression in particular is real and meaningful — most people naturally and significantly reduce how much food they’re eating, often without even trying. Here’s where it gets interest
The Next Wave of GLP-1s Is Coming
Score 0.594
· Account tjphuhs@gmail.com
· 3/31/2026, 6:05:53 PM
The Next Wave of GLP-1s Is Coming from huntershealthhacks@mail.beehiiv.com on 2026-03-31T22:05:53.000Z restores mitochondrial function. These are effects that GLP-1 agonism alone cannot replicate. When glucagon agonism is combined with GLP-1 agonism in a single molecule, the GLP-1 component counterbalances the glucose-raising effect of glucagon. No increased risk of hyperglycemia has been observed in trials of either compound. ——————————————————————————— **The Benefits ** The weight loss numbers
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption?
Score 0.591
· Account tjphuhs@gmail.com
· 4/25/2026, 9:07:43 PM
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption? from tjphuhs@gmail.com on 2026-04-26T01:07:43.000Z on top of an already-slowed system. Fat-heavy meals can sit particularly long, which is part of why high-fat meals tend to produce the worst GI side effects on these protocols. > Specific Nutrient Issues That Have Popped Up > This is where the rubber meets the road. Across the broader GLP-1 user base — both clinical and community-reported — certain nutrient deficienc
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption?
Score 0.591
· Account oc.tjphuhs@gmail.com
· 4/25/2026, 9:07:43 PM
Fwd: GLP-1s and Slowed Gastric Emptying Part 2: What About Nutrient Absorption? from tjphuhs@gmail.com on 2026-04-26T01:07:43.000Z on top of an already-slowed system. Fat-heavy meals can sit particularly long, which is part of why high-fat meals tend to produce the worst GI side effects on these protocols. > Specific Nutrient Issues That Have Popped Up > This is where the rubber meets the road. Across the broader GLP-1 user base — both clinical and community-reported — certain nutrient deficienc
Fwd: GLP-1s and Slowed Gastric Emptying: What It Means for Compound Absorption
Score 0.590
· Account oc.tjphuhs@gmail.com
· 4/25/2026, 9:08:09 PM
Fwd: GLP-1s and Slowed Gastric Emptying: What It Means for Compound Absorption from tjphuhs@gmail.com on 2026-04-26T01:08:09.000Z > The compounds where this PK shift becomes noteworthy in the published literature are the ones where timing of the peak is part of the mechanism, or where a sharp Cmax is what produces the intended effect: > Fast-onset agents where the curve shape is the effect — the onset profile changes, and the shifted Tmax can create the impression that something isn’t working wh
Fwd: GLP-1s and Slowed Gastric Emptying: What It Means for Compound Absorption
Score 0.590
· Account tjphuhs@gmail.com
· 4/25/2026, 9:08:09 PM
Fwd: GLP-1s and Slowed Gastric Emptying: What It Means for Compound Absorption from tjphuhs@gmail.com on 2026-04-26T01:08:09.000Z > The compounds where this PK shift becomes noteworthy in the published literature are the ones where timing of the peak is part of the mechanism, or where a sharp Cmax is what produces the intended effect: > Fast-onset agents where the curve shape is the effect — the onset profile changes, and the shifted Tmax can create the impression that something isn’t working wh
Massive GLP-1 Data From ECO 2026
Score 0.590
· Account tjphuhs@gmail.com
· 5/13/2026, 10:52:49 AM
Massive GLP-1 Data From ECO 2026 from onthepen@substack.com on 2026-05-13T14:52:49.000Z weeks. Two cohorts: those coming off Zepbound and those coming off Wegovy. 376 participants total. They started orforglipron at 12mg and titrated up every four weeks, targeting a maximum of 36mg. A rescue protocol allowed escalation or a switch from placebo to orforglipron after week 24 for anyone who regained more than half their original loss. One detail to keep in mind: there was a two-week screening gap b