Email Archive

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.816 · Account oc.tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z ---------- Forwarded message ---------- From: Hunter Williams <huntershealthhacks@mail.beehiiv.com> Date: Apr 24, 2026 at 6:06 PM -0400 To: tjphuhs@gmail.com <tjphuhs@gmail.com> Subject: Autoimmune, Fertility, and GLP-1s > New podcast is live! > April 24, 2026 | Read online > Autoimmune, Fertility, and GLP-1s > New podcast is live! > > > > Happy Friday! > A new episode of the podcast just dropped today. > T

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.816 · Account tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z ---------- Forwarded message ---------- From: Hunter Williams <huntershealthhacks@mail.beehiiv.com> Date: Apr 24, 2026 at 6:06 PM -0400 To: tjphuhs@gmail.com <tjphuhs@gmail.com> Subject: Autoimmune, Fertility, and GLP-1s > New podcast is live! > April 24, 2026 | Read online > Autoimmune, Fertility, and GLP-1s > New podcast is live! > > > > Happy Friday! > A new episode of the podcast just dropped today. > T

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.774 · Account oc.tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z Axion Collective. > Thanks for watching, listening, sharing, and supporting us. None of this happens without you! > Have a great weekend! > Best, > Hunter Williams > Want more? Here’s how you can work with me: > 👉Join my private coaching group, The AXION Collective: > > • > The AXION Collective > > 👉Try Zeroats, the world’s first sugar-free, naturally flavored oatmeal: > > • > Store: https://zeroats.com/

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.774 · Account tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z Axion Collective. > Thanks for watching, listening, sharing, and supporting us. None of this happens without you! > Have a great weekend! > Best, > Hunter Williams > Want more? Here’s how you can work with me: > 👉Join my private coaching group, The AXION Collective: > > • > The AXION Collective > > 👉Try Zeroats, the world’s first sugar-free, naturally flavored oatmeal: > > • > Store: https://zeroats.com/

GLP-1s vs. Fertility

Score 0.746 · Account tjphuhs@gmail.com · 5/4/2026, 6:05:41 PM

GLP-1s vs. Fertility from huntershealthhacks@mail.beehiiv.com on 2026-05-04T22:05:41.000Z Happy Monday! Taylor and I are trying to have a baby. As I do with most everything in my life, I research as much as I can to achieve the desired outcome. Studies I used to skim now feel much more personal. And the one that's been on my mind lately is from Dr. Shanna Swan. If you haven't read her book _Countdown_, here's the short version. Sperm concentration in Western men decreased by more than 50% betwee

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.742 · Account tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z and cancer. Probably the most controversial topic on the list. We got questions about whether peptides are safe after breast cancer treatment, whether growth hormone peptides raise cancer risk, and whether PNC-27 should be run proactively. > I share why I don't personally worry about the cancer risk with peptides, why testosterone gets completely ignored in the breast cancer conversation, and what I'd actua

Fwd: Autoimmune, Fertility, and GLP-1s

Score 0.742 · Account oc.tjphuhs@gmail.com · 4/25/2026, 9:08:42 PM

Fwd: Autoimmune, Fertility, and GLP-1s from tjphuhs@gmail.com on 2026-04-26T01:08:42.000Z and cancer. Probably the most controversial topic on the list. We got questions about whether peptides are safe after breast cancer treatment, whether growth hormone peptides raise cancer risk, and whether PNC-27 should be run proactively. > I share why I don't personally worry about the cancer risk with peptides, why testosterone gets completely ignored in the breast cancer conversation, and what I'd actua

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.730 · Account oc.tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z of trying everything else. For many others, it was the first real hope offered, after the promises of metabolic surgeries failed to deliver as promised. > That is exactly why pregnancy can add such a complex layer to the journey, because the same medication that helped restore metabolic health is also restoring ovulation in ways many women using GLP-1 therapies did not necessarily

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.730 · Account tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z of trying everything else. For many others, it was the first real hope offered, after the promises of metabolic surgeries failed to deliver as promised. > That is exactly why pregnancy can add such a complex layer to the journey, because the same medication that helped restore metabolic health is also restoring ovulation in ways many women using GLP-1 therapies did not necessarily

Autoimmune, Fertility, and GLP-1s

Score 0.726 · Account tjphuhs@gmail.com · 4/24/2026, 6:05:34 PM

Autoimmune, Fertility, and GLP-1s from huntershealthhacks@mail.beehiiv.com on 2026-04-24T22:05:34.000Z Happy Friday! A new episode of the podcast just dropped today. Taylor is back with me, and we did another reader mailbag episode based on all the amazing questions you guys write in (you can always submit questions [here](https://hunterwilliamsvideotopic.carrd.co/)). Youtube: Reader Mailbag 2 — Autoimmune, Fertility, Cancer & More | Hunter & Taylor Williams (https://youtu.be/tcaX0xrCMR4) You ca

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.723 · Account tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: Mar 28, 2026 at 1:38 PM -0400 To: tjphuhs@gmail.com Subject: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In > If you’re currently on a GLP-1, or if you’ve been on one long enough to feel your body experience massive changes, you already understand why this conversatio

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.723 · Account oc.tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z ---------- Forwarded message ---------- From: Dave Knapp from On The Pen <onthepen@substack.com> Date: Mar 28, 2026 at 1:38 PM -0400 To: tjphuhs@gmail.com Subject: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In > If you’re currently on a GLP-1, or if you’ve been on one long enough to feel your body experience massive changes, you already understand why this conversatio

GLP-1s vs. Fertility

Score 0.714 · Account tjphuhs@gmail.com · 5/4/2026, 6:05:41 PM

GLP-1s vs. Fertility from huntershealthhacks@mail.beehiiv.com on 2026-05-04T22:05:41.000Z ovarian steroidogenesis, granulosa cell biology, and the FSH-cAMP-BMP signaling pathway. It's likely a direct ovarian effect layered on top of metabolic improvement. ——————————————————————————— **Microdosing for Fertility** Here's where I'm going to get speculative. Most of the GLP-1 fertility research uses standard or high doses. The kind aimed at meaningful weight loss. 1mg semaglutide weekly. 3mg liraglu

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.708 · Account tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z There is one small pharmacokinetic study involving Semaglutide that did not detect transfer into breast milk, but the patient pool was small, and more studies will likely be necessary for many clinicians to feel comfortable giving GLP-1 use during lactation the “thumbs up”. > READ ABOUT THE LACTATION STUDY > The biggest gap across all of this is duration, and that is where the unce

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.708 · Account oc.tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z There is one small pharmacokinetic study involving Semaglutide that did not detect transfer into breast milk, but the patient pool was small, and more studies will likely be necessary for many clinicians to feel comfortable giving GLP-1 use during lactation the “thumbs up”. > READ ABOUT THE LACTATION STUDY > The biggest gap across all of this is duration, and that is where the unce

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.706 · Account tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z and this is not some small corner of the audience. This is a huge group of women who have spent years being told their condition was secondary to weight instead of something with its own biology and its own set of levers. In the review, GLP-1 therapies were associated with improvements in both metabolic and reproductive markers in women with PCOS, including signals around insulin r

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.706 · Account oc.tjphuhs@gmail.com · 4/7/2026, 1:00:10 PM

Fwd: GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from tjphuhs@gmail.com on 2026-04-07T17:00:10.000Z and this is not some small corner of the audience. This is a huge group of women who have spent years being told their condition was secondary to weight instead of something with its own biology and its own set of levers. In the review, GLP-1 therapies were associated with improvements in both metabolic and reproductive markers in women with PCOS, including signals around insulin r

Autoimmune, Fertility, and GLP-1s

Score 0.703 · Account tjphuhs@gmail.com · 4/24/2026, 6:05:34 PM

Autoimmune, Fertility, and GLP-1s from huntershealthhacks@mail.beehiiv.com on 2026-04-24T22:05:34.000Z I'd actually use if I wanted a proactive anti-cancer cycle once or twice a year. ——————————————————————————— **Healthy seniors and statins.** I told the story of Taylor's dad. 80 pounds overweight, A1C of nine or ten, on statins for "perfect cholesterol." I told him to throw the statins in the trash and start testosterone. Three months later, his A1C dropped two points, and his cholesterol stay

Fwd: New Study Worth Knowing About: GLP-1s and Alzheimer's

Score 0.699 · Account tjphuhs@gmail.com · 4/30/2026, 11:00:22 AM

Fwd: New Study Worth Knowing About: GLP-1s and Alzheimer's from tjphuhs@gmail.com on 2026-04-30T15:00:22.000Z wave of trials needs to recruit at-risk people before symptoms start — that’s where the real test happens. > This is one more data point worth tracking as the field develops. Stay measured, watch the next 2-3 years of trial readouts, and don’t get ahead of the evidence. > Drop questions or thoughts below. > Disclaimer: This content is for research and educational purposes only and is not

Fwd: New Study Worth Knowing About: GLP-1s and Alzheimer's

Score 0.699 · Account oc.tjphuhs@gmail.com · 4/30/2026, 11:00:22 AM

Fwd: New Study Worth Knowing About: GLP-1s and Alzheimer's from tjphuhs@gmail.com on 2026-04-30T15:00:22.000Z wave of trials needs to recruit at-risk people before symptoms start — that’s where the real test happens. > This is one more data point worth tracking as the field develops. Stay measured, watch the next 2-3 years of trial readouts, and don’t get ahead of the evidence. > Drop questions or thoughts below. > Disclaimer: This content is for research and educational purposes only and is not

GLP-1s vs. Fertility

Score 0.691 · Account tjphuhs@gmail.com · 5/4/2026, 6:05:41 PM

GLP-1s vs. Fertility from huntershealthhacks@mail.beehiiv.com on 2026-05-04T22:05:41.000Z all. For couples whose fertility is being dragged down by metabolic dysfunction, GLP-1s are the most promising pharmacological lever I've seen in a decade. The female data on PCOS pregnancy rates is the strongest signal in the whole literature. The male data is catching up. The next 24 months of trial data will tell us a lot. I'll keep you posted on what we learn, on our journey, and on the science. GLP-1s

GLP-1s vs. Fertility

Score 0.691 · Account tjphuhs@gmail.com · 5/4/2026, 6:05:41 PM

GLP-1s vs. Fertility from huntershealthhacks@mail.beehiiv.com on 2026-05-04T22:05:41.000Z but the question is whether the clinical data back it up. ——————————————————————————— **The Male Data** In a 2023 trial, La Vignera and colleagues gave liraglutide to obese men with metabolic hypogonadism and severe erectile dysfunction. After 4 months, semen concentration, motility, and morphology all significantly improved. Erectile function scores improved more than with conventional fertility treatment

GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In

Score 0.667 · Account tjphuhs@gmail.com · 3/28/2026, 1:38:29 PM

GLP-1 Pregnancy Fears vs Reality… The First Real Data Is In from onthepen@substack.com on 2026-03-28T17:38:29.000Z View this post on the web at https://onthepen.substack.com/p/glp-1-pregnancy-fears-vs-reality If you’re currently on a GLP-1, or if you’ve been on one long enough to feel your body experience massive changes, you already understand why this conversation matters. These are not casual medications for this community, they are often the first thing that actually moved the needle after y

Do GLP-1s Kill Your Testosterone?

Score 0.662 · Account tjphuhs@gmail.com · 4/28/2026, 10:43:24 AM

Do GLP-1s Kill Your Testosterone? from derekpruski@substack.com on 2026-04-28T14:43:24.000Z (STEP 1) Tirzepatide: ~21% loss at 72 weeks (SURMOUNT-1) Peptide-R (triple-agonist): ~24% at 48 weeks (phase 2), and 28.7% at 68 weeks in the recent phase 3 TRIUMPH-4 readout. Placebo-adjusted: 26.6%. Once weight loss gets that aggressive, you’re no longer just dropping fat — you’re forcing the body into sustained caloric deficit territory that the HPG axis interprets as famine. And the famine response is

New Study Worth Knowing About: GLP-1s and Alzheimer's

Score 0.660 · Account tjphuhs@gmail.com · 4/30/2026, 10:19:32 AM

New Study Worth Knowing About: GLP-1s and Alzheimer's from derekpruski@substack.com on 2026-04-30T14:19:32.000Z below. Disclaimer: This content is for research and educational purposes only and is not medical advice. All compounds discussed (peptides, GLP-1 receptor agonists, and related research chemicals) are referenced in the context of research use only (RUO) and the published scientific literature. Nothing in this post should be interpreted as a recommendation for human consumption, diagnos