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Semantic Search: AMD’s spike reveals CPUs’ importance
AMD’s spike reveals CPUs’ importance
Score 0.805
· Account tjphuhs@gmail.com
· 5/7/2026, 6:42:03 AM
AMD’s spike reveals CPUs’ importance from hello@snacks.robinhood.com on 2026-05-07T10:42:03.000Z 96 AMD’s spike reveals just how central CPUs are to the AI boom   Hey Snackers, Goodbye Jeeves… Ask.com (formerly askjeeves.𝖼𝗈𝗆) has shut down after almost 30 years of operation. Debuting in 1996, a whole year before Google, it wasn’t too long before search-and-answer stalwarts like Alphabet ’s engine and Yahoo overtook Jeeves — which are now themselves getting overshadowed by AI. See how th
AMD’s spike reveals CPUs’ importance
Score 0.799
· Account tjphuhs@gmail.com
· 5/7/2026, 6:42:03 AM
AMD’s spike reveals CPUs’ importance from hello@snacks.robinhood.com on 2026-05-07T10:42:03.000Z on the performance of peers, the industry at large. It’s not just AMD: In its fiscal Q4 2026 earnings report last night, Arm Holdings reported a deluge of demand for its data center CPUs, which were launched in late March . “We now have more than $2 billion of customer demand across fiscal 2027 and fiscal 2028, more than double what we stated at launch,” per the press release. “Soon the data center w
AMD’s spike reveals CPUs’ importance
Score 0.710
· Account tjphuhs@gmail.com
· 5/7/2026, 6:42:03 AM
AMD’s spike reveals CPUs’ importance from hello@snacks.robinhood.com on 2026-05-07T10:42:03.000Z Off the charts What is America’s favorite planet , according to a new YouGov survey? (Before you say it, Pluto is indeed included as a planet in the survey.) Check your answer .   What else we're Snackin' Corning spiked after Nvidia invested $500 million in the fiber-optics maker , a bet that could dwarf the chip designer’s other recent connectivity plays Crypto is blossoming with green shoots
Fwd: MOTS-c & Morning Workout Timing — A Beginner-Friendly Breakdown
Score 0.558
· Account tjphuhs@gmail.com
· 3/21/2026, 1:06:18 PM
Fwd: MOTS-c & Morning Workout Timing — A Beginner-Friendly Breakdown from tjphuhs@gmail.com on 2026-03-21T17:06:18.000Z — often called the “powerhouse of the cell.” MOTS-c is essentially a signal that mitochondria send out to communicate with the rest of the body about energy status. > In research, it has shown strong effects on metabolism, insulin sensitivity, fat utilization, and cellular energy regulation. > Two Pathways You Need to Understand > To understand why timing matters, a researcher
High Performance Rate Limiting at Databricks
Score 0.551
· Account tjphuhs@gmail.com
· 5/13/2026, 11:30:35 AM
High Performance Rate Limiting at Databricks from bytebytego@substack.com on 2026-05-13T15:30:35.000Z View this post on the web at https://blog.bytebytego.com/p/high-performance-rate-limiting-at ScyllaDB Founders Share What Real-Time AI Requires from the Database (Sponsored) [ https://substack.com/redirect/cc973a24-c008-4be2-a06b-86d5eca83aba?j=eyJ1IjoiNGl3b2U2In0.sVDxRtmZ85v8kfdamY0krRXGMy3p768BWtuZifRB-Zs ] AI is pushing databases to their limits; learn what it takes to stay ahead AI workloads
Adamax & Adalank: Two Upgrades, Two Very Different Reasons
Score 0.544
· Account tjphuhs@gmail.com
· 4/8/2026, 3:54:02 PM
Adamax & Adalank: Two Upgrades, Two Very Different Reasons from derekpruski@substack.com on 2026-04-08T19:54:02.000Z produces to regulate mood and stress), extending their active window Immune system support — retained from Selank’s origins as a tuftsin analog (tuftsin is a naturally occurring immune peptide), including cytokine regulation (cytokines are signaling proteins that coordinate immune responses) and broader immune system modulation The upgrade Adalank represents is pharmacokinetic — m
Will Tesla shareholders take off for SpaceX stock?
Score 0.543
· Account tjphuhs@gmail.com
· 5/11/2026, 6:43:54 AM
Will Tesla shareholders take off for SpaceX stock? from hello@snacks.robinhood.com on 2026-05-11T10:43:54.000Z of industry leaders before they become household names. Innovators like NVIDIA, Netflix, Starbucks, and JetBlue Airways all started as mid-cap holdings. Get to know MDY . ZOOM OUT Stories we’re obsessed with The rise and fall of Duolingo : Investors were hoping Duolingo could be an artificial intelligence winner — AI would boost its content output, optimize learning, and open up new lan
Synergy Over Maximalism: The Part of Stacking Nobody Talks About
Score 0.543
· Account tjphuhs@gmail.com
· 3/25/2026, 11:46:44 AM
Synergy Over Maximalism: The Part of Stacking Nobody Talks About from derekpruski@substack.com on 2026-03-25T15:46:44.000Z chain. It also activates sirtuins — proteins that regulate mitochondrial health, DNA repair, and cellular stress responses. NAD+ levels decline significantly with age in research subjects, and when they drop, mitochondrial function follows. Restoring NAD+ in research replenishes a core substrate the whole system depends on. SLU-PP-332 SLU-PP-332 is an ERR (estrogen-related r
The Double-Edged Sword of Dopamine
Score 0.542
· Account tjphuhs@gmail.com
· 5/11/2026, 6:04:20 PM
The Double-Edged Sword of Dopamine from huntershealthhacks@mail.beehiiv.com on 2026-05-11T22:04:20.000Z spike at the moment of food retrieval. Classic reward signal. The kind of release that says "yes, do that again." Mice on liraglutide, danuglipron, and orforglipron all showed the same thing. A flatter peak. A smaller sustained release. **Less dopamine, period.** This was true for all three drugs, peptide and small molecule alike. Which means it's a class effect, not specific to one compound.
The Brain Peptide You Don't Know About
Score 0.539
· Account tjphuhs@gmail.com
· 1/27/2026, 6:09:49 PM
The Brain Peptide You Don't Know About from huntershealthhacks@mail.beehiiv.com on 2026-01-27T23:09:49.000Z plasticity. Mechanistically, it is associated with pathways like JAK/STAT3, MAPK, and PI3K/Akt, which are heavily involved in how neurons adapt and survive under stress. One of the signature concepts around P21 is LIF inhibition, meaning it interferes with leukemia inhibitory factor signaling. LIF signaling can suppress aspects of neurogenesis, and P21 appears to reduce that brake, allowin
This Tiny SSD Is 13x Faster 😱
Score 0.538
· Account tjphuhs@gmail.com
· 5/12/2026, 7:02:04 PM
This Tiny SSD Is 13x Faster 😱 from support@metapcs.com on 2026-05-12T23:02:04.000Z [Content Tuesday!](http://www.tiktok.com/@metapcsonline/) This Tiny SSD Is 13x Faster 😱 [Watch it here:](#) [Watch on TikTok](https://www.tiktok.com/@metapcsonline/video/7637825328802516255) [Watch on Youtube](https://www.youtube.com/shorts/z2N8k5iWk_w) [Watch on Instagram](https://www.instagram.com/p/DYH0WSeh_K0/) [Watch on Facebook](https://web.facebook.com/reel/996805042786117) New GPU But Same FPS!? [Watch o
Fwd: 9-Me-BC: The Nootropic That Wakes Up Your Brain's Own Reward System
Score 0.537
· Account tjphuhs@gmail.com
· 3/20/2026, 10:11:53 AM
Fwd: 9-Me-BC: The Nootropic That Wakes Up Your Brain's Own Reward System from tjphuhs@gmail.com on 2026-03-20T14:11:53.000Z — or 9-Me-BC — is a naturally occurring compound in the beta-carboline family. Beta-carbolines are found in small amounts in certain foods and even produced endogenously (your body makes trace amounts of them). 9-Me-BC specifically has been the subject of growing research interest because of what it appears to do to dopaminergic neurons — the cells in your brain responsible
Fwd: 9-Me-BC: The Nootropic That Wakes Up Your Brain's Own Reward System
Score 0.537
· Account oc.tjphuhs@gmail.com
· 3/20/2026, 10:11:53 AM
Fwd: 9-Me-BC: The Nootropic That Wakes Up Your Brain's Own Reward System from tjphuhs@gmail.com on 2026-03-20T14:11:53.000Z — or 9-Me-BC — is a naturally occurring compound in the beta-carboline family. Beta-carbolines are found in small amounts in certain foods and even produced endogenously (your body makes trace amounts of them). 9-Me-BC specifically has been the subject of growing research interest because of what it appears to do to dopaminergic neurons — the cells in your brain responsible
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.534
· Account oc.tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z 20.1% weight loss at 48 weeks in Phase 2 — as a standalone drug. Novo Nordisk’s CagriSema combines semaglutide with an amylin agonist for this exact reason. Amylin is a proven target. > Calcitonin > This is the most interesting addition, and the one most worth understanding in depth. > Calcitonin is a hormone your thyroid produces that’s been known for decades primarily
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.534
· Account tjphuhs@gmail.com
· 4/24/2026, 9:42:34 AM
Fwd: Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from tjphuhs@gmail.com on 2026-04-24T13:42:34.000Z 20.1% weight loss at 48 weeks in Phase 2 — as a standalone drug. Novo Nordisk’s CagriSema combines semaglutide with an amylin agonist for this exact reason. Amylin is a proven target. > Calcitonin > This is the most interesting addition, and the one most worth understanding in depth. > Calcitonin is a hormone your thyroid produces that’s been known for decades primarily
Why Fasted Administration Actually Matters — The Full Breakdown
Score 0.533
· Account tjphuhs@gmail.com
· 3/22/2026, 7:51:55 AM
Why Fasted Administration Actually Matters — The Full Breakdown from derekpruski@substack.com on 2026-03-22T11:51:55.000Z while those with GH maintained a much more favorable balance — highlighting GH’s critical role in preserving lean tissue during a fasted or deficit state. This is the combination the RS is trying to create: low insulin, elevated GH, fat cells releasing stored fat, and that fat getting burned as fuel. Each piece of the fasted state sets up the next one. Why This Matters for Fa
How AI is bringing dead voices back
Score 0.532
· Account tjphuhs@gmail.com
· 5/14/2026, 7:10:37 AM
How AI is bringing dead voices back from hello@snacks.robinhood.com on 2026-05-14T11:10:37.000Z 96 AI is giving life to a resurrection economy (Getty Images)   Presented by Hey Snackers, What are the most popular baby names? New data from the Social Security Administration found that Olivia and Liam were again the top picks for baby girls and boys — marking the seventh straight year that Olivia’s been No. 1 for girls, and the ninth where Liam has been the top pick for American boys. We cha
Fwd: Synergy Over Maximalism: The Part of Stacking Nobody Talks About
Score 0.531
· Account oc.tjphuhs@gmail.com
· 3/25/2026, 12:17:01 PM
Fwd: Synergy Over Maximalism: The Part of Stacking Nobody Talks About from tjphuhs@gmail.com on 2026-03-25T16:17:01.000Z strategy, you need to understand what each of these compounds does at the cellular level in research contexts. Don’t worry — keeping it simple. > Mitochondria are the power plants of cells. They take in nutrients and convert them into ATP — the actual energy currency cells run on. When mitochondrial function declines, everything suffers: energy, cognition, recovery, metabolism
Fwd: Synergy Over Maximalism: The Part of Stacking Nobody Talks About
Score 0.531
· Account tjphuhs@gmail.com
· 3/25/2026, 12:17:01 PM
Fwd: Synergy Over Maximalism: The Part of Stacking Nobody Talks About from tjphuhs@gmail.com on 2026-03-25T16:17:01.000Z strategy, you need to understand what each of these compounds does at the cellular level in research contexts. Don’t worry — keeping it simple. > Mitochondria are the power plants of cells. They take in nutrients and convert them into ATP — the actual energy currency cells run on. When mitochondrial function declines, everything suffers: energy, cognition, recovery, metabolism
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine
Score 0.529
· Account tjphuhs@gmail.com
· 4/24/2026, 9:05:46 AM
Eli Lilly’s Quintuple Agonist: The Next Frontier in Metabolic Medicine from derekpruski@substack.com on 2026-04-24T13:05:46.000Z have better tolerability than incretins, with less nausea Lilly’s eloralintide (a selective amylin agonist) showed up to 20.1% weight loss at 48 weeks in Phase 2 — as a standalone drug. Novo Nordisk’s CagriSema combines semaglutide with an amylin agonist for this exact reason. Amylin is a proven target. Calcitonin This is the most interesting addition, and the one most
Urolithin A: The Most Underrated Compound in Longevity
Score 0.529
· Account tjphuhs@gmail.com
· 5/2/2026, 11:16:56 AM
Urolithin A: The Most Underrated Compound in Longevity from derekpruski@substack.com on 2026-05-02T15:16:56.000Z which collectively drive expression of antioxidant defense genes and reduce oxidative stress. Mechanisms Relevant to Neurodegeneration This is the section that doesn’t get enough attention. UA crosses the blood-brain barrier, and the preclinical neuroprotective data is genuinely impressive across multiple disease models. Alzheimer’s disease (preclinical) In multiple AD mouse models —
Fwd: NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend
Score 0.528
· Account tjphuhs@gmail.com
· 3/27/2026, 4:33:04 PM
Fwd: NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend from tjphuhs@gmail.com on 2026-03-27T20:33:04.000Z every cell in your body. Their job is to take the food you eat and convert it into usable energy. When they work well, you feel it — better energy, better metabolism, better recovery. When they decline, everything suffers. > This blend targets mitochondrial function from three different angles at the same time. Each compound has its own job, but they work together in a way that makes the
Fwd: NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend
Score 0.528
· Account oc.tjphuhs@gmail.com
· 3/27/2026, 4:33:04 PM
Fwd: NAD+ / MOTS-c / 5-Amino-1MQ: Breaking Down The Blend from tjphuhs@gmail.com on 2026-03-27T20:33:04.000Z every cell in your body. Their job is to take the food you eat and convert it into usable energy. When they work well, you feel it — better energy, better metabolism, better recovery. When they decline, everything suffers. > This blend targets mitochondrial function from three different angles at the same time. Each compound has its own job, but they work together in a way that makes the
Database Selection in AI-Powered Software Engineering
Score 0.525
· Account tjphuhs@gmail.com
· 5/11/2026, 2:00:11 PM
Database Selection in AI-Powered Software Engineering from techscoop@substack.com on 2026-05-11T18:00:11.000Z +----------------------+ | +----------------------+ | Distributed SQL DB | +----------------------+ / | \ / | \ +---------+ +---------+ +---------+ | Node 1 | | Node 2 | | Node 3 | +---------+ +---------+ +---------+ Use Cases NewSQL databases are ideal for: Financial platforms Global SaaS applications Real-time analytics High-concurrency applications For example, Google Spanner powers g
GHK-Cu: Morning or Night — Does Timing Matter for Your Research?
Score 0.525
· Account tjphuhs@gmail.com
· 4/7/2026, 11:20:35 AM
GHK-Cu: Morning or Night — Does Timing Matter for Your Research? from derekpruski@substack.com on 2026-04-07T15:20:35.000Z shown the ability to upregulate superoxide dismutase (SOD) and other protective enzymes. Superoxide dismutase is one of the body’s most important internal antioxidant enzymes — its job is to neutralize free radicals, which are unstable molecules that damage cells over time. Upregulating SOD means the body is producing more of its own natural defense against that damage Gene