Subject: He took Retatrutide 40mg and Proved a Point
From: Dave Knapp from On The Pen <[email-masked]>
To: [email-masked]
Date: Tue, 5 May 2026 23:44:17 +0000
List-Id: <onthepen.substack.com>

View this post on the web at https://onthepen.substack.com/p/he-took-retatrutide-40mg-and-proved

Forty milligrams of Retatrutide. That’s the number and the mistake that sets the tone for this week’s episode. A 32-year-old man bought the drug online, started at 10 milligrams, quickly escalated to 20, and then accidentally dosed twice in back-to-back days. You can imagine how that ended, and we break it all down on the podcast.
At the same time, just one month into the Foundayo launch, there’s already a reported case of liver failure. 
Two very different situations, but if you’ve been following On The Pen, you’ll start to see the connection. This episode pulls those threads together and points toward something just as important: how patients can better track, understand, and stay ahead of what’s happening on their own GLP-1 journey. 
Keep scrolling to check out Shed’s new GLP-1 journey tracking app that’s available to anyone!
One theme keeps coming up: understanding what’s actually happening in your own body matters just as much as following the prescription. It’s something we’ve been thinking more about lately, how people track their progress, notice patterns, and make sense of changes in hunger, energy, or cravings over time. Tools like Pivot are starting to make that easier, bringing doses, daily habits, and personal feedback into one place so adjustments feel more informed and less like guesswork.
Pivot is a new app offered to anyone, even if you don’t get your prescriptions through Shed.
• Track doses, weight, and daily habits in one place
• See your full history and compare how you feel across different doses
• Connect changes in hunger, energy, and cravings to your medication
• Weekly success score + insights to guide what to adjust next
It’s a smarter way to stay in tune with your body. If you want to try it out, you can download it here!

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