Subject: Results from my Feb 23 skin therapy:
From: Bryan Johnson from Bryan Johnson <[email-masked]>
To: [email-masked]
Date: Tue, 7 Apr 2026 00:42:28 +0000
List-Id: <bryanjohns0n.substack.com>

View this post on the web at https://bryanjohns0n.substack.com/p/results-from-my-feb-23-skin-therapy

Improvements since treatment:
> Brown spots: +71 percentile points (20th → 91st)✅
> Pores: +25 percentile points✅
> Spots: +25 percentile points✅
My skin age is 9 years younger than my chronological age (39 vs 48) and hasn’t aged in five years since starting this project. Effectively a 9 year age reversal. Measured using VISIA multispectral clinical imaging, the most validated non-invasive skin analysis system available.
Feb 23 treatment summary
Technologies
>  Everesse RF
> CoolPeel CO2 laser
> BBL
Each targeting a different skin depth so repair windows overlap without competing.
Treatment details
Everesse RF (200 pulses, Level 2.5 per cheek), CoolPeel CO2 laser (3.0W, 700 micron spacing), and BBL broadband light. Each targeting a different skin depth. 
Everesse drives heat into the dermis at 60-70°C, triggering fibroblast activation and collagen production that peaks 6-8 weeks later (about now), tightening the structural scaffolding that makes pores visible. 
CoolPeel ablates the surface layer of skin, physically removing melanin-loaded cells and forcing fresh keratinocytes to the surface. 
BBL destroys residual pigment one layer deeper through selective photothermolysis, where melanin absorbs light energy and self-destructs. 
Porphyrins dropped 13 points, which is expected. The treatments temporarily disrupt the follicular environment that bacteria need to thrive, and that recovers within 8-12 weeks. 
Goal was to do a triple-modality stack so the repair windows overlap without competing (dermis, epidermis, and chromophores).

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