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[161.38.194.182]) by mx.google.com with UTF8SMTPS id d75a77b69052e-50b36e9403esi152691541cf.215.2026.03.23.09.50.31 for (version=TLS1_2 cipher=ECDHE-ECDSA-AES128-GCM-SHA256 bits=128/128); Mon, 23 Mar 2026 09:50:32 -0700 (PDT) Received-SPF: pass (google.com: domain of bounce+91e48a.63af5d-tjphuhs=gmail.com@mg-d0.substack.com designates 161.38.194.182 as permitted sender) client-ip=161.38.194.182; Authentication-Results: mx.google.com; dkim=pass header.i=@mg-d0.substack.com header.s=mailo header.b=b1JY75Wt; dkim=pass header.i=@mailgun.org header.s=mg header.b=Kn6dJi66; spf=pass (google.com: domain of bounce+91e48a.63af5d-tjphuhs=gmail.com@mg-d0.substack.com designates 161.38.194.182 as permitted sender) smtp.mailfrom="bounce+91e48a.63af5d-tjphuhs=gmail.com@mg-d0.substack.com"; dmarc=pass (p=REJECT sp=REJECT dis=NONE) header.from=substack.com DKIM-Signature: a=rsa-sha256; v=1; c=relaxed/relaxed; d=mg-d0.substack.com; q=dns/txt; s=mailo; t=1774284631; x=1774291831; h=List-Unsubscribe-Post: List-Unsubscribe: List-Post: List-Id: List-Archive: List-Owner: Reply-To: In-Reply-To: References: Sender: Sender: Date: Message-Id: To: To: From: From: Subject: Subject: Content-Type: Mime-Version: X-Feedback-Id; bh=0pQNH08DANGdd7n92d9ftJMar3QUZhpEKWco41NYP6E=; b=b1JY75WtwJ1iQMpjhlUf3kEUn1dgEC1NFcsJ2zo9VT+JWPXhIc34wVcx3Y2ZlCywPQLl0N1mu/UXyK0maLtiqJVFt9r6Y8MpNcBvF0Iu85+JyGAyYsoPPARKBB88quhBOyjTr+jqOFq4VJojs4ej4V2+iBAmvNcTZGixD1ijN9Q= DKIM-Signature: a=rsa-sha256; v=1; c=relaxed/relaxed; d=mailgun.org; q=dns/txt; s=mg; t=1774284631; x=1774291831; h=List-Unsubscribe-Post: List-Unsubscribe: List-Post: List-Id: List-Archive: List-Owner: Reply-To: In-Reply-To: References: Sender: Sender: Date: Message-Id: To: To: From: From: Subject: Subject: Content-Type: Mime-Version: X-Feedback-Id; bh=0pQNH08DANGdd7n92d9ftJMar3QUZhpEKWco41NYP6E=; b=Kn6dJi66Rx/TYuWIJRlTIbmzoWfAQu22gMB/lCEdgvW0qsPR7axeApS2ubrKtiyjBhf3eyk7/lkR5a1En91RthRiF1/sqnXBztHt3oUAuDYCBkYEzhbxWQSz41P6gs/fWt75kS0kQDDGq2sjwGcwDLSNFQBa+M/nh2KMjfFvCO8= X-Mailgun-Sid: WyJkZWU4NyIsInRqcGh1aHNAZ21haWwuY29tIiwiNjNhZjVkIl0= X-Feedback-Id: postmaster@mg-d0.substack.com:post:6148c7d8a45790427cda307f:mailgun Received: by 34c9e6ad235bbba83fd8e8f629481658eb2710fb465e47f13ad2d8b7fbdf56f7 with HTTP id 69c16f5757efc09328419673; Mon, 23 Mar 2026 16:50:31 GMT X-Mailgun-Sending-Ip: 161.38.194.182 Mime-Version: 1.0 Content-Type: multipart/alternative; boundary="8fbac6bf393eb59e469da68a70ea2a637a5a3f63214f9462b524fb1d9477" Subject: Semax, Selank & SSRIs: What the Research Says About Combining Them From: Derek from Peptide Price To: tjphuhs@gmail.com X-Mailgun-Tag: post X-Mailgun-Track-Clicks: false Message-Id: <20260323165025.3.263ae442ad35bb23@mg-d0.substack.com> Date: Mon, 23 Mar 2026 16:50:25 +0000 Feedback-Id: post-191886015:cat-post:pub-3365367:substack Sender: Derek from Peptide Price References: In-Reply-To: Reply-To: Derek from Peptide Price List-Owner: List-Url: List-Archive: List-Id: List-Post: List-Unsubscribe: List-Unsubscribe-Post: List-Unsubscribe=One-Click X-Mailgun-Variables: {"category": "post", "email_generated_at": "1774284631218", "is_freemail": "true", "post_audience": "everyone", "post_id": "191886015", "post_type": "newsletter", "pub_community_enabled": "true", "publication_id": "3365367", "subdomain": "derekpruski", "user_id": "273622398"} --8fbac6bf393eb59e469da68a70ea2a637a5a3f63214f9462b524fb1d9477 Content-Type: text/plain; charset="utf-8" Content-Transfer-Encoding: quoted-printable View this post on the web at https://derekpruski.substack.com/p/semax-selan= k-and-ssris-what-the-research For research and educational purposes only. Not for human consumption. Not = medical advice. I get asked about SSRIs constantly. Every nootropic peptide post, every Q&A= , every comment section. =E2=80=9CCan I use this on an SSRI?=E2=80=9D =E2= =80=9CWill this interact with my antidepressant?=E2=80=9D =E2=80=9CIs it sa= fe to combine?=E2=80=9D It=E2=80=99s the most common question in the nootropic space =E2=80=94 and = it deserves a real answer, not a blanket =E2=80=9Ctalk to your doctor=E2=80= =9D and nothing else. So let=E2=80=99s start here, with the two nootropic peptides I get this que= stion about the most: Semax and Selank. They=E2=80=99re the most studied no= otropic peptides in this category, they both interact with the serotonin sy= stem in some capacity, and they=E2=80=99re genuinely different from each ot= her in ways that matter for this conversation. This is not medical advice. Do not make changes to any prescription medicat= ion without talking to your prescribing physician. That part is non-negotia= ble =E2=80=94 but it doesn=E2=80=99t mean we can=E2=80=99t look at the mech= anisms and have an informed conversation about what the research actually s= hows. What These Peptides Actually Do Before getting into interactions, a quick recap on mechanisms. Semax is derived from a fragment of ACTH =E2=80=94 a hormone your brain pro= duces naturally as part of the stress response. Researchers modified that f= ragment to remove the hormonal activity and amplify the neurological effect= s. The result is a peptide that primarily works by upregulating BDNF =E2=80= =94 brain-derived neurotrophic factor. BDNF is essentially fertilizer for y= our neurons. It supports their growth and survival, strengthens synaptic co= nnections, and plays a central role in learning, memory, and cognitive resi= lience. Beyond BDNF, Semax also modulates dopaminergic and serotonergic sig= naling =E2=80=94 influencing how dopamine and serotonin are released and ut= ilized in key brain regions. Research interest centers on cognitive enhance= ment, neuroprotection, and focus. Selank is derived from tuftsin, an immune peptide the body produces natural= ly. Its primary mechanism is GABAergic modulation =E2=80=94 it influences t= he GABA system, which is the brain=E2=80=99s main inhibitory (calming) netw= ork. It also affects enkephalins, which are endogenous opioid peptides invo= lved in mood and stress regulation. And like Semax, Selank has a documented= interaction with serotonin metabolism =E2=80=94 research has found it can = slow the enzymatic breakdown of serotonin in certain brain regions, effecti= vely increasing serotonin availability. Research interest centers on anxiet= y reduction, stress resilience, and cognitive clarity under pressure. The short version: Semax skews stimulating and cognitively activating, driv= en mainly by BDNF and dopamine. Selank skews calming and anxiolytic, driven= mainly by GABA and serotonin preservation. How SSRIs Work SSRIs =E2=80=94 selective serotonin reuptake inhibitors =E2=80=94 block the= reuptake of serotonin in the synaptic cleft. When a neuron fires and relea= ses serotonin, that serotonin would normally get pulled back into the sendi= ng neuron relatively quickly. SSRIs block that transporter, so serotonin li= ngers in the synapse longer, increasing serotonergic signaling over time. C= ommon examples: sertraline (Zoloft), fluoxetine (Prozac), escitalopram (Lex= apro), paroxetine (Paxil). The concern is reasonable =E2=80=94 if both peptides interact with serotoni= n in some way, and SSRIs are directly targeting that same system, is there = potential for amplification, interference, or something more serious? Yes, there=E2=80=99s theoretical overlap. But the nature of that overlap is= more nuanced than most people assume. Where the Overlap Actually Exists Selank carries the more direct serotonin overlap. Research has found it red= uces the activity of enzymes responsible for breaking down serotonin =E2=80= =94 effectively increasing serotonin availability through a degradation pat= hway. This is mechanistically distinct from what SSRIs do (which act on the= reuptake transporter), but the net direction is the same: both push toward= elevated serotonergic activity. The concern this raises is serotonin syndrome =E2=80=94 a condition caused = by excessive serotonergic stimulation, ranging from mild (restlessness, ele= vated heart rate, sweating) to severe. That said, serotonin syndrome most c= ommonly results from combining multiple agents that each directly and poten= tly target the serotonin system. Selank=E2=80=99s effect on serotonin is co= mparatively mild and indirect =E2=80=94 it=E2=80=99s not hitting the reupta= ke transporter the way an SSRI does. There is no published research documen= ting serotonin syndrome from Selank combined with SSRIs, and no known case = reports in the literature. The combination shouldn=E2=80=99t be dismissed outright =E2=80=94 but it al= so shouldn=E2=80=99t be treated as equivalent to stacking two direct seroto= nergic drugs. The more practical flag is this: someone on an SSRI for clini= cal anxiety or depression is already pharmacologically treating a condition= that Selank is being researched to address. Layering the two without physi= cian awareness is not a reasonable approach. Semax carries less direct serotonin overlap. Research shows Semax modulates= serotonin release in a region-specific way, but its primary mechanism is B= DNF =E2=80=94 and BDNF has a well-documented relationship with serotonergic= systems in the antidepressant literature. BDNF upregulation is actually on= e of the proposed long-term mechanisms by which SSRIs produce their effects= =2E This means Semax=E2=80=99s interaction= with the serotonin system may actu= ally run more parallel to =E2=80=94 and complementary with =E2=80=94 SSRI m= echanisms rather than against them. The dopaminergic effects of Semax are largely independent of SSRI pathways,= which is where most of its stimulating and focus-related research properti= es originate. The Realistic Picture There is no published clinical research specifically examining Semax + SSRI= or Selank + SSRI combinations in humans. That=E2=80=99s the honest startin= g point. What exists is mechanistic inference =E2=80=94 an understanding of= what each compound does individually, and where those pathways logically i= ntersect. Based on that: Selank + SSRI carries more theoretical serotonergic overlap, primarily due = to Selank=E2=80=99s influence on serotonin degradation. The risk isn=E2=80= =99t equivalent to combining two direct serotonergic drugs, but it=E2=80=99= s not zero either =E2=80=94 and anyone on an SSRI should not be adding Sela= nk to any research protocol without their physician=E2=80=99s awareness. Semax + SSRI is a lower-concern combination from a serotonin standpoint. Th= e BDNF pathway Semax primarily acts through has been studied in the context= of supporting antidepressant efficacy, not competing with it. The dopamine= rgic activity is largely orthogonal to SSRI mechanisms. In both cases =E2=80=94 physician involvement isn=E2=80=99t optional. These= are research peptides with no human clinical trial data on SSRI co-adminis= tration. Only a physician with full knowledge of the medication picture can= make a responsible call. General Precaution Semax is the lower-overlap option. Its core mechanisms =E2=80=94 BDNF upreg= ulation, dopaminergic modulation, neuroprotection =E2=80=94 run largely par= allel to SSRI pathways rather than through them. Selank is the higher-overlap option, specifically because of its serotonin = degradation mechanism. That doesn=E2=80=99t make it dangerous by default, b= ut it makes physician consultation more important before any research invol= ving the combination. SSRIs are not supplements. They=E2=80=99re prescription medications managin= g a neurological condition, and adding anything that touches the serotonin = system without the prescribing physician=E2=80=99s knowledge is not a risk = worth taking. More SSRI + nootropic peptide breakdowns coming. If there=E2=80=99s a speci= fic compound you want covered next, drop it in the comments. =E2=80=94 Derek All content is for educational and research purposes only. Research subject= s in all discussed contexts are non-human. Nothing here constitutes medical= advice or a recommendation to change, add, or discontinue any medication o= r treatment protocol. Unsubscribe https://substack.com/redirect/2/eyJlIjoiaHR0cHM6Ly9kZXJla3BydXN= raS5zdWJzdGFjay5jb20vYWN0aW9uL2Rpc2FibGVfZW1haWw_dG9rZW49ZXlKMWMyVnlYMmxrSW= pveU56TTJNakl6T1Rnc0luQnZjM1JmYVdRaU9qRTVNVGc0TmpBeE5Td2lhV0YwSWpveE56YzBNa= mcwTmpNeExDSmxlSEFpT2pFNE1EVTRNakEyTXpFc0ltbHpjeUk2SW5CMVlpMHpNelkxTXpZM0lp= d2ljM1ZpSWpvaVpHbHpZV0pzWlY5bGJXRnBiQ0o5LnlrNHkxQ3k0WGNaRkFIamFaQWcwaVJ2U1h= fQ1BvV2YtMzZham9nOFV4UDQiLCJwIjoxOTE4ODYwMTUsInMiOjMzNjUzNjcsImYiOnRydWUsIn= UiOjI3MzYyMjM5OCwiaWF0IjoxNzc0Mjg0NjMxLCJleHAiOjIwODk4NjA2MzEsImlzcyI6InB1Y= i0wIiwic3ViIjoibGluay1yZWRpcmVjdCJ9.0Sul4jTQyggOgd-2b2xXXA88wdcxOB-CGoj4pji= k-w0? --8fbac6bf393eb59e469da68a70ea2a637a5a3f63214f9462b524fb1d9477 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: quoted-printable Semax, Selank & SSRI= s: What the Research Says About Combining Them3D""
For research and educational purposes only.
͏     = ­͏     ­͏     ­͏  =   ­͏     ­͏     ­T= 7;     ­͏     ­͏     &= #173;͏     ­͏     ­͏   =   ­͏     ­͏     ­͏= ;     ­͏     ­͏     &#= 173;͏     ­͏     ­͏   &= #8199; ­͏     ­͏     ­͏=     ­͏     ­͏     = 73;͏     ­͏     ­͏   &#= 8199; ­͏     ­͏     ­͏ =     ­͏     ­͏     = 3;͏     ­͏     ­͏   = 199; ­͏     ­͏     ­͏ &= nbsp;   ­͏     ­͏     ­= ;͏     ­͏     ­͏   Q= 99; ­͏     ­͏     ­͏ &n= bsp;   ­͏     ­͏     ­= ͏     ­͏     ­͏   ̳= 9; ­͏     ­͏     ­͏ &nb= sp;   ­͏     ­͏     ­&= #847;     ­͏     ­͏    = ; ­͏     ­͏     ­͏ &nbs= p;   ­͏     ­͏     ­&#= 847;     ­͏     ­͏    = ­͏     ­͏     ­͏  = ;   ­͏     ­͏     ­= 47;     ­͏     ­͏     = ­͏     ­͏     ­͏  =   ­͏     ­͏     ­T= 7;     ­͏     ­͏     &= #173;͏     ­͏     ­͏   =   ­͏     ­͏     ­͏= ;     ­͏     ­͏     &#= 173;͏     ­͏     ­͏   &= #8199; ­͏     ­͏     ­͏=     ­͏     ­͏     = 73;͏     ­͏     ­͏   &#= 8199; ­͏     ­͏     ­͏ =     ­͏     ­͏     = 3;͏     ­͏     ­͏   = 199; ­͏     ­͏     ­͏ &= nbsp;   ­͏     ­͏     ­= ;͏     ­͏     ­͏   Q= 99; ­͏     ­͏     ­͏ &n= bsp;   ­͏     ­͏     ­= ͏     ­͏     ­͏   ̳= 9; ­͏     ­͏     ­͏ &nb= sp;   ­͏     ­͏     ­&= #847;     ­͏     ­͏    = ; ­͏     ­͏     ­͏ &nbs= p;   ­͏     ­͏     ­&#= 847;     ­͏     ­͏    = ­͏     ­͏     ­͏  = ;   ­͏     ­͏     ­= 47;     ­͏     ­͏     = ­͏     ­͏     ­͏  =   ­͏     ­͏     ­T= 7;     ­͏     ­͏     &= #173;͏     ­͏     ­͏   =   ­͏     ­͏     ­͏= ;     ­͏     ­͏     &#= 173;͏     ­͏     ­͏   &= #8199; ­͏     ­͏     ­͏=     ­͏     ­͏     = 73;͏     ­͏     ­͏   &#= 8199; ­͏     ­͏     ­͏ =     ­͏     ­͏     = 3;͏     ­͏     ­͏   = 199; ­͏     ­͏     ­͏ &= nbsp;   ­͏     ­͏     ­= ;͏     ­͏     ­͏   Q= 99; ­͏     ­͏     ­͏ &n= bsp;   ­͏     ­͏     ­= ͏     ­
<= /tbody>
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Semax, Selank & SSRIs: What the Research Says= About Combining Them

Derek
 
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<= table role=3D"presentation" width=3D"38" border=3D"0" cellspacing=3D"0" cel= lpadding=3D"0">
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READ IN APP<= img class=3D"icon text-icon" src=3D"https://substackcdn.com/image/fetch/$s_= !ET-_!,w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsu= bstack.com%2Ficon%2FLucideArrowUpRight%3Fv%3D4%26height%3D36%26fill%3Dnone%= 26stroke%3D%2523808080%26strokeWidth%3D2" width=3D"18" height=3D"18" style= =3D"min-width: 18px;min-height: 18px;border: none;vertical-align: middle;ma= rgin-right: 0;margin-left: 0;max-width: 18px" alt=3D"">
&nb= sp;

For = research and educational purposes only. Not for human consumption. Not medi= cal advice.

I get asked about SSRIs constantly. Every no= otropic peptide post, every Q&A, every comment section. “Can I us= e this on an SSRI?” “Will this interact with my antidepressant?= ” “Is it safe to combine?”

It’s the= most common question in the nootropic space — and it deserves a real= answer, not a blanket “talk to your doctor” and nothing else.<= /p>

So let’s start here, with the two nootropic peptides = I get this question about the most: Semax and Selank. They’re the mos= t studied nootropic peptides in this category, they both interact with the = serotonin system in some capacity, and they’re genuinely different fr= om each other in ways that matter for this conversation.

Th= is is not medical advice. Do not make changes to any prescription medicatio= n without talking to your prescribing physician. That part is non-negotiabl= e — but it doesn’t mean we can’t look at the mechanisms a= nd have an informed conversation about what the research actually shows.

3D""
Upgrade to paid
What These Peptides Actually Do

Bef= ore getting into interactions, a quick recap on mechanisms.

Semax is derived from a fragment of ACTH — a = hormone your brain produces naturally as part of the stress response. Resea= rchers modified that fragment to remove the hormonal activity and amplify t= he neurological effects. The result is a peptide that primarily works by up= regulating BDNF — brain-derived neurotrophic factor. BDNF is essentia= lly fertilizer for your neurons. It supports their growth and survival, str= engthens synaptic connections, and plays a central role in learning, memory= , and cognitive resilience. Beyond BDNF, Semax also modulates dopaminergic = and serotonergic signaling — influencing how dopamine and serotonin a= re released and utilized in key brain regions. Research interest centers on= cognitive enhancement, neuroprotection, and focus.

= Selank is derived from tuftsin, an immune peptide th= e body produces naturally. Its primary mechanism is GABAergic modulation &#= 8212; it influences the GABA system, which is the brain’s main inhibi= tory (calming) network. It also affects enkephalins, which are endogenous o= pioid peptides involved in mood and stress regulation. And like Semax, Sela= nk has a documented interaction with serotonin metabolism — research = has found it can slow the enzymatic breakdown of serotonin in certain brain= regions, effectively increasing serotonin availability. Research interest = centers on anxiety reduction, stress resilience, and cognitive clarity unde= r pressure.

The short version: Semax skews stimulati= ng and cognitively activating, driven mainly by BDNF and dopamine. Selank s= kews calming and anxiolytic, driven mainly by GABA and serotonin preservati= on.

<= /div>

How SSRIs Work

SSRIs — selective= serotonin reuptake inhibitors — block the reuptake of serotonin in t= he synaptic cleft. When a neuron fires and releases serotonin, that seroton= in would normally get pulled back into the sending neuron relatively quickl= y. SSRIs block that transporter, so serotonin lingers in the synapse longer= , increasing serotonergic signaling over time. Common examples: sertraline = (Zoloft), fluoxetine (Prozac), escitalopram (Lexapro), paroxetine (Paxil).<= /p>

The concern is reasonable — if both peptides interact= with serotonin in some way, and SSRIs are directly targeting that same sys= tem, is there potential for amplification, interference, or something more = serious?

Yes, there’s theoretical overlap. But the na= ture of that overlap is more nuanced than most people assume.

Where the Overlap Actually Exists

Selank carrie= s the more direct serotonin overlap. Research has found it r= educes the activity of enzymes responsible for breaking down serotonin R= 12; effectively increasing serotonin availability through a degradation pat= hway. This is mechanistically distinct from what SSRIs do (which act on the= reuptake transporter), but the net direction is the same: both push toward= elevated serotonergic activity.

The concern this ra= ises is serotonin syndrome — a condition caused by excessive serotone= rgic stimulation, ranging from mild (restlessness, elevated heart rate, swe= ating) to severe. That said, serotonin syndrome most commonly results from = combining multiple agents that each directly and potently target the seroto= nin system. Selank’s effect on serotonin is comparatively mild and in= direct — it’s not hitting the reuptake transporter the way an S= SRI does. There is no published research documenting serotonin syndrome fro= m Selank combined with SSRIs, and no known case reports in the literature.<= /p>

The combination shouldn’t be dismissed outright ̵= 2; but it also shouldn’t be treated as equivalent to stacking two dir= ect serotonergic drugs. The more practical flag is this: someone on an SSRI= for clinical anxiety or depression is already pharmacologically treating a= condition that Selank is being researched to address. Layering the two wit= hout physician awareness is not a reasonable approach.

Semax carries less direct serotonin overlap. Research sh= ows Semax modulates serotonin release in a region-specific way, but its pri= mary mechanism is BDNF — and BDNF has a well-documented relationship = with serotonergic systems in the antidepressant literature. BDNF upregulati= on is actually one of the proposed long-term mechanisms by which SSRIs prod= uce their effects. This means Semax’s interaction with the serotonin = system may actually run more parallel to — and complementary with = 212; SSRI mechanisms rather than against them.

The d= opaminergic effects of Semax are largely independent of SSRI pathways, whic= h is where most of its stimulating and focus-related research properties or= iginate.

The Realistic Picture

There is no= published clinical research specifically examining Semax + SSRI or Selank = + SSRI combinations in humans. That’s the honest starting point. What= exists is mechanistic inference — an understanding of what each comp= ound does individually, and where those pathways logically intersect.

Based on that:

Selank + SSRI carries more theore= tical serotonergic overlap, primarily due to Selank’s influence on se= rotonin degradation. The risk isn’t equivalent to combining two direc= t serotonergic drugs, but it’s not zero either — and anyone on = an SSRI should not be adding Selank to any research protocol without their = physician’s awareness.

Semax + SSRI is a lower-concer= n combination from a serotonin standpoint. The BDNF pathway Semax primarily= acts through has been studied in the context of supporting antidepressant = efficacy, not competing with it. The dopaminergic activity is largely ortho= gonal to SSRI mechanisms.

In both cases — physician i= nvolvement isn’t optional. These are research peptides with no human = clinical trial data on SSRI co-administration. Only a physician with full k= nowledge of the medication picture can make a responsible call.

General Precaution

Semax is the lower-overlap option= =2E Its core mechanisms — BDNF up= regulation, dopaminergic modulation, n= europrotection — run largely parallel to SSRI pathways rather than th= rough them.

Selank is the higher-overlap option, specifical= ly because of its serotonin degradation mechanism. That doesn’t make = it dangerous by default, but it makes physician consultation more important= before any research involving the combination.

SSRIs are n= ot supplements. They’re prescription medications managing a neurologi= cal condition, and adding anything that touches the serotonin system withou= t the prescribing physician’s knowledge is not a risk worth taking.

More SSRI + nootropic peptide breakdowns coming. If there= 217;s a specific compound you want covered next, drop it in the comments.

— Derek

All content is for education= al and research purposes only. Research subjects in all discussed contexts = are non-human. Nothing here constitutes medical advice or a recommendation = to change, add, or discontinue any medication or treatment protocol.

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