Return-Path: Received: from [2607:fb91:8c16:ca31::f0:ffff] ([2607:fb91:8c16:ca31:ad97:bb20:67c0:e079]) by smtp.gmail.com with ESMTPSA id 00721157ae682-79a905ba0a9sm2285147b3.46.2026.03.19.12.17.28 for (version=TLS1_2 cipher=ECDHE-ECDSA-AES128-GCM-SHA256 bits=128/128); Thu, 19 Mar 2026 12:17:29 -0700 (PDT) Date: Thu, 19 Mar 2026 15:17:25 -0400 From: tjphuhs@gmail.com To: "=?utf-8?Q?oc.tjphuhs=40gmail.com?=" Message-ID: <573f6b82-5f2d-43e9-a318-d339e7fc7a79@Spark> In-Reply-To: <20260319190133.3.25a37174aebba8c5@mg2.substack.com> References: <20260319190133.3.25a37174aebba8c5@mg2.substack.com> Subject: Fwd: Tesamorelin Degradation Baseline vs Month 1 | Room Temp vs Refrigerated | Peptide Crafters X-Readdle-Message-ID: 573f6b82-5f2d-43e9-a318-d339e7fc7a79@Spark MIME-Version: 1.0 Content-Type: multipart/alternative; boundary="69bc4bc8_393e0a75_200b" --69bc4bc8_393e0a75_200b Content-Type: text/plain; charset="utf-8" Content-Transfer-Encoding: quoted-printable Content-Disposition: inline ---------- =46orwarded message ---------- =46rom: Derek from Peptide Price Date: Mar 19, 2026 at 3:02=E2=80=AFPM -0400 To: tjphuhs=40gmail.com Subject: Tesamorelin Degradation Baseline vs Month 1 =7C Room Temp vs Ref= rigerated =7C Peptide Crafters > Earlier today I shared a sneak peek at the first month of Peptide Craft= ers=E2=80=99 Tesamorelin degradation study. > =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 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=C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0= =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2= =AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2= =A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87= =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F= =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80= =87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD= =8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2= =80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD= =CD=8F =C2=A0 =E2=80=87 =C2=AD=CD=8F =C2=A0 =E2=80=87 =C2=AD > =46orwarded this email=3F Subscribe here for more > Tesamorelin Degradation Baseline vs Month 1 =7C Room Temp vs Refrigerat= ed =7C Peptide Crafters > Derek > Mar 19 > > READ IN APP > > Earlier today I shared a sneak peek at the first month of Peptide Craft= ers=E2=80=99 Tesamorelin degradation study. Shortly after they got back t= o me with the baseline COA, so now we can do a proper comparison. Here=E2= =80=99s the full breakdown. > Most people in this space know they should store their peptides properl= y but have never actually seen data showing what happens when you don=E2=80= =99t. This study starts to answer that question with real numbers from a = controlled comparison. > Study Setup > Same batch (PC-G2-TS10), three samples tested by Janoshik on =46ebruary= 16, 2026 to establish a starting point =E2=80=94 think of this as the =E2= =80=9Cbefore=E2=80=9D snapshot. Two months of additional testing still to= come. > Here=E2=80=99s how the timeline worked before that baseline test even h= appened: the samples were produced, spent about a week in dry storage at = the facility, then shipped to Janoshik which took another week. So by the= time Janoshik tested them for baseline, they had already been sitting in= lyophilized (freeze-dried powder) form for roughly two weeks. Once basel= ine was confirmed, each sample was assigned to its storage condition and = the clock started. > Storage conditions: > > =E2=80=A2 > Sample B =E2=80=94 room temperature at 68=E2=80=9370=C2=B0=46= > =E2=80=A2 > Sample C =E2=80=94 frozen at -39=C2=B0=46 > =E2=80=A2 > Sample A =E2=80=94 held for later timepoints in the study > > One thing worth flagging for context: most researchers store peptides i= n a standard household fridge running around 35=E2=80=9340=C2=B0=46. The = =E2=80=9Crefrigerated=E2=80=9D condition here is actually a freezer at -3= 9=C2=B0=46, which is colder than what most people are working with at hom= e. The real-world difference between room temperature and a standard frid= ge may be a bit smaller than what this study shows =E2=80=94 but the dire= ction of the results will almost certainly be the same. > Baseline =E2=80=94 =46ebruary 16, 2026 > > =E2=80=A2 > Sample A =E2=80=94 10.76 mg =7C Purity: 99.894% > =E2=80=A2 > Sample B =E2=80=94 11.46 mg =7C Purity: 99.876% > =E2=80=A2 > Sample C =E2=80=94 10.90 mg =7C Purity: 99.861% > > All three samples started in essentially the same place =E2=80=94 purit= y right around 99.86=E2=80=9399.89%. That=E2=80=99s a clean, consistent s= tarting point across the board. > Month 1 Results =E2=80=94 March 16, 2026 > Sample B (Room Temperature =E2=80=94 68=E2=80=9370=C2=B0=46) > > =E2=80=A2 > Baseline: 11.46 mg =7C 99.876% > =E2=80=A2 > Month 1: 10.81 mg =7C 98.184% > =E2=80=A2 > Content loss: 0.65 mg (-5.67%) > =E2=80=A2 > Purity loss: 1.692 percentage points > > Sample C (=46rozen =E2=80=94 -39=C2=B0=46) > > =E2=80=A2 > Baseline: 10.90 mg =7C 99.861% > =E2=80=A2 > Month 1: 10.59 mg =7C 99.732% > =E2=80=A2 > Content loss: 0.31 mg (-2.84%) > =E2=80=A2 > Purity loss: 0.129 percentage points > > What The Numbers Actually Mean > Think of purity as how much of what=E2=80=99s in the vial is actually t= he peptide you want versus broken down byproducts. The higher the number = the better. > After one month in the freezer, Sample C dropped only 0.129 percentage = points in purity and lost 0.31 mg of content. That=E2=80=99s essentially = nothing =E2=80=94 the peptide is nearly identical to where it started. > Sample B stored at room temperature is a different story. It lost 0.65 = mg of content =E2=80=94 more than twice what the frozen sample lost =E2=80= =94 and dropped 1.692 percentage points in purity. That=E2=80=99s over 13= times more purity degradation than the frozen sample over the exact same= period from the exact same batch. > In plain terms: if your Tesamorelin sits at room temperature for a mont= h, it is measurably less potent and less pure than when you started. Cold= storage largely prevents that. > The narrative that refrigerating or freezing Tesamorelin causes degrada= tion has never had real data behind it. One month in, the frozen sample i= s sitting at 99.732% purity with minimal content loss. That talking point= should be put to rest =E2=80=94 and two more months of data will make it= even more definitive. > Where The Study Goes =46rom Here > This is month one of three. The real value here is the full progression= =E2=80=94 two more months of data will show whether the degradation rate= stays steady, speeds up, or levels off. Peptide degradation doesn=E2=80=99= t always move in a straight line, which is exactly why tracking it over m= ultiple months matters. > If the gap between room temperature and frozen continues to widen throu= gh months two and three, the cumulative difference is going to be substan= tial. I=E2=80=99ll share the data as each round comes in. > Big shoutout to Peptide Crafters for running this properly and letting = me share it with the community in real time. > Upgrade to paid > You're currently a free subscriber to Peptide Price. =46or the full exp= erience, upgrade your subscription. > Upgrade to paid > > Share > > > Like > Comment > Restack > > =C2=A9 2026 Derek Pruski > 548 Market Street PMB 72296, San =46rancisco, CA 94104 > Unsubscribe --69bc4bc8_393e0a75_200b Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: quoted-printable Content-Disposition: inline
---------- =46orwarded message ----= ------
=46rom: Derek from Peptide Price <derekpruski=40substack.com>= ;
Date: Mar 19, 2026 at 3:02=E2=80=AFPM -0400
To: tjphuhs=40gmail.com
Subject: Tesamorelin Degradation Baseline vs Month 1 =7C Room Temp= vs Refrigerated =7C Peptide Crafters

=3D=22=22
Earlier today I shared a sneak peek at the first month of Peptid= e Crafters=E2=80=99 Tesamorelin degradation study.
=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23= 160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80= =87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD= =CD=8F &=23160; =E2=80=87 =C2=AD=CD=8F &=23160; =E2=80=87 =C2=AD
=46orwarded this email=3F Subscribe here for more<= /span>

Tesamorelin Degradation Baseline vs Month 1 =7C Room Temp vs Refrigerate= d =7C Peptide Crafters

Derek
&=23160;=
3D=22=22
3D=22=22
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3D=22=22=
READ IN APP3D=
&=23160;=

Earlier today I shared a sneak peek at t= he first month of Peptide Crafters=E2=80=99 Tesamorelin degradation study= . Shortly after they got back to me with the baseline COA, so now we can = do a proper comparison. Here=E2=80=99s the full breakdown.

Most people in this space know they should store their= peptides properly but have never actually seen data showing what happens= when you don=E2=80=99t. This study starts to answer that question with r= eal numbers from a controlled comparison.

Study Setup

Same batch (PC-G2-TS10), three samples tested by Janos= hik on =46ebruary 16, 2026 to establish a starting point =E2=80=94 think = of this as the =E2=80=9Cbefore=E2=80=9D snapshot. Two months of additiona= l testing still to come.

Here=E2=80=99s how the timeline worked before that bas= eline test even happened: the samples were produced, spent about a week i= n dry storage at the facility, then shipped to Janoshik which took anothe= r week. So by the time Janoshik tested them for baseline, they had alread= y been sitting in lyophilized (freeze-dried powder) form for roughly two = weeks. Once baseline was confirmed, each sample was assigned to its stora= ge condition and the clock started.

Storage conditions:

  • Sampl= e B =E2=80=94 room temperature at 68=E2=80=9370=C2=B0=46

  • Sampl= e C =E2=80=94 frozen at -39=C2=B0=46

  • Sampl= e A =E2=80=94 held for later timepoints in the study

One thing worth flagging for context: most researchers= store peptides in a standard household fridge running around 35=E2=80=93= 40=C2=B0=46. The =E2=80=9Crefrigerated=E2=80=9D condition here is actuall= y a freezer at -39=C2=B0=46, which is colder than what most people are wo= rking with at home. The real-world difference between room temperature an= d a standard fridge may be a bit smaller than what this study shows =E2=80= =94 but the direction of the results will almost certainly be the same.

Baseline =E2=80=94 =46ebruary 16, 2026

  • Sampl= e A =E2=80=94 10.76 mg =7C Purity: 99.894%

  • Sampl= e B =E2=80=94 11.46 mg =7C Purity: 99.876%

  • Sampl= e C =E2=80=94 10.90 mg =7C Purity: 99.861%

3D=22image.png=22

All three samples started in essentially the same plac= e =E2=80=94 purity right around 99.86=E2=80=9399.89%. That=E2=80=99s a cl= ean, consistent starting point across the board.

Month 1 Results =E2=80=94 March 16, 2026

Sample B (Room Temperature =E2=80=94 68=E2=80=9370=C2=B0= =46)

  • Basel= ine: 11.46 mg =7C 99.876%

  • Month= 1: 10.81 mg =7C 98.184%

  • Conte= nt loss: 0.65 mg (-5.67%)

  • Purit= y loss: 1.692 percentage points

3D=22image.png=22

Sample C (=46rozen =E2=80=94 -39=C2=B0=46)

  • Basel= ine: 10.90 mg =7C 99.861%

  • Month= 1: 10.59 mg =7C 99.732%

  • Conte= nt loss: 0.31 mg (-2.84%)

  • Purit= y loss: 0.129 percentage points

3D=22image.png=22

What The Numbers Actually Mean

Think of purity as how much of what=E2=80=99s in the v= ial is actually the peptide you want versus broken down byproducts. The h= igher the number the better.

After one month in the freezer, Sample C dropped only = 0.129 percentage points in purity and lost 0.31 mg of content. That=E2=80= =99s essentially nothing =E2=80=94 the peptide is nearly identical to whe= re it started.

Sample B stored at room temperature is a different sto= ry. It lost 0.65 mg of content =E2=80=94 more than twice what the frozen = sample lost =E2=80=94 and dropped 1.692 percentage points in purity. That= =E2=80=99s over 13 times more purity degradation than the frozen sample o= ver the exact same period from the exact same batch.

In plain terms: if your Tesamorelin sits at room tempe= rature for a month, it is measurably less potent and less pure than when = you started. Cold storage largely prevents that.

The narrative that refrigerating or freezing Tesamorel= in causes degradation has never had real data behind it. One month in, th= e frozen sample is sitting at 99.732% purity with minimal content loss. T= hat talking point should be put to rest =E2=80=94 and two more months of = data will make it even more definitive.

Where The Study Goes =46rom Here

This is month one of three. The real value here is the= full progression =E2=80=94 two more months of data will show whether the= degradation rate stays steady, speeds up, or levels off. Peptide degrada= tion doesn=E2=80=99t always move in a straight line, which is exactly why= tracking it over multiple months matters.

If the gap between room temperature and frozen continu= es to widen through months two and three, the cumulative difference is go= ing to be substantial. I=E2=80=99ll share the data as each round comes in= .

Big shoutout to Peptide Crafters for running this prop= erly and letting me share it with the community in real time.

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You're= currently a free subscriber to Peptide Price. =46or the full experience, upgrade your subscription.

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=C2=A9 2026 Derek Pruski
548 Market Street PMB 72296, San =46rancisco, CA 94104
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