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From: TJ Bourdeau <tjphuhs@gmail.com>
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Date: Tue, 17 Mar 2026 17:51:48 -0400
Subject: Fwd: Compound Tirzepatide & Semaglutide Updates!
Message-Id: <7942F7BD-C998-4000-819D-7829A993223C@gmail.com>
References: <20260317200346.3.293e32084164e18d@mg-d1.substack.com>
To: oc.tjphuhs@gmail.com
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v=3D"content-type" content=3D"text/html; charset=3Dutf-8"></head><body dir=3D=
"auto"><br id=3D"lineBreakAtBeginningOfSignature"><div dir=3D"ltr">TJ</div><=
div dir=3D"ltr"><br>Begin forwarded message:<br><br></div><blockquote type=3D=
"cite"><div dir=3D"ltr"><b>From:</b> Dave Knapp from On The Pen &lt;onthepen=
@substack.com&gt;<br><b>Date:</b> March 17, 2026 at 4:03:57=E2=80=AFPM EDT<b=
r><b>To:</b> tjphuhs@gmail.com<br><b>Subject:</b> <b>Compound Tirzepatide &a=
mp; Semaglutide Updates!</b><br><b>Reply-To:</b> Dave Knapp from On The Pen &=
lt;reply+35w1tf&amp;4iwoe6&amp;&amp;9985d0eabdad8d3ee001e8d18022b7e3ec1f9e03=
481cf6e0f518cbf32ac3e62e@mg1.substack.com&gt;<br><br></div></blockquote><blo=
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der-radius: 9999px;text-transform: uppercase;font-size: 12px;line-height: 1;=
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;box-sizing: border-box;width: 38px"><img class=3D"icon" src=3D"https://subs=
tackcdn.com/image/fetch/$s_!5EGt!,w_36,c_scale,f_png,q_auto:good,fl_progress=
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r></tbody></table></td><td align=3D"right"><table role=3D"presentation" widt=
h=3D"auto" border=3D"0" cellspacing=3D"0" cellpadding=3D"0"><tbody><tr><td s=
tyle=3D"vertical-align:middle;"><table role=3D"presentation" width=3D"auto" b=
order=3D"0" cellspacing=3D"0" cellpadding=3D"0"><tbody><tr><td align=3D"cent=
er"><a class=3D"email-button-outline" href=3D"https://open.substack.com/pub/=
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nline-block;font-weight: 500;border: 1px solid rgb(0,0,0,.1);border-radius: 9=
999px;text-transform: uppercase;font-size: 12px;line-height: 12px;padding: 9=
px 14px;text-decoration: none;color: rgb(119,119,119);"><div class=3D"email-=
button-spacer" style=3D"font-size: 16px;line-height: 26px;display: inline-bl=
ock;vertical-align: middle;max-width: 0;min-height: 18px;"></div><span class=
=3D"email-button-text" style=3D"vertical-align: middle;margin-right: 4px">RE=
AD IN APP</span><img class=3D"icon text-icon" src=3D"https://substackcdn.com=
/image/fetch/$s_!ET-_!,w_36,c_scale,f_png,q_auto:good,fl_progressive:steep/h=
ttps%3A%2F%2Fsubstack.com%2Ficon%2FLucideArrowUpRight%3Fv%3D4%26height%3D36%=
26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2" width=3D"18" height=3D=
"18" style=3D"min-width: 18px;min-height: 18px;border: none;vertical-align: m=
iddle;margin-right: 0;margin-left: 0;max-width: 18px" alt=3D"" data-unique-i=
dentifier=3D""></a></td></tr></tbody></table></td></tr></tbody></table></td>=
</tr></tbody></table></td></tr><tr height=3D"16"><td height=3D"16" style=3D"=
font-size:0px;line-height:0;">&nbsp;</td></tr></tbody></table></div></div><d=
iv class=3D"post typography" dir=3D"auto" style=3D"--image-offset-margin: -1=
20px;padding: 32px 0 0 0;font-size: 16px;line-height: 26px;"><div class=3D"b=
ody markup" dir=3D"auto" style=3D"text-align: initial;font-size: 16px;line-h=
eight: 26px;width: 100%;word-break: break-word;margin-bottom: 16px;font-fami=
ly: 'SF Pro Display', -apple-system, system-ui, BlinkMacSystemFont, 'Inter',=
 'Segoe UI', Roboto, Helvetica, Arial, sans-serif, 'Apple Color Emoji', 'Seg=
oe UI Emoji', 'Segoe UI Symbol';font-weight: 400;"><p style=3D"margin: 0 0 2=
0px 0;color: rgb(54,55,55);line-height: 26px;font-size: 16px;margin-top: 0;"=
>Happy Spring Break to many of you! While Dave and I are taking a short brea=
k from MFW LIVE this week, the news is anything but quiet. Major development=
s are unfolding, and you can catch up on everything in the latest OTP podcas=
t, where Dave breaks it all down.</p><a class=3D"youtube-wrap" href=3D"https=
://substack.com/redirect/af25770a-d14d-443c-8b07-5164cd172b43?j=3DeyJ1IjoiNG=
l3b2U2In0.sVDxRtmZ85v8kfdamY0krRXGMy3p768BWtuZifRB-Zs" target=3D"_blank" dat=
a-component-name=3D"Youtube2ToDOMStatic" style=3D"display: block;margin: 32p=
x 0;"><img src=3D"https://substackcdn.com/image/youtube/w_728,c_limit/l_yout=
ube_play_qyqt8q,w_120/PKQPu0zWTe4" style=3D"border: none !important;vertical=
-align: middle;-ms-interpolation-mode: bicubic;max-width: 100%;height: auto;=
margin: 0 auto;display: block;width: 100%;" data-unique-identifier=3D""></a>=
<p style=3D"margin: 0 0 20px 0;color: rgb(54,55,55);line-height: 26px;font-s=
ize: 16px;">In today=E2=80=99s episode, Dave explores several important topi=
cs, including:</p><ul style=3D"margin-top: 0;padding: 0;"><li style=3D"margi=
n: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D"color: rgb(54,55,55=
);line-height: 26px;margin-bottom: 0;box-sizing: border-box;padding-left: 4p=
x;font-size: 16px;margin: 0;">Massive compound shakeup</p></li><li style=3D"=
margin: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D"color: rgb(54,=
55,55);line-height: 26px;margin-bottom: 0;box-sizing: border-box;padding-lef=
t: 4px;font-size: 16px;margin: 0;">Why compound users need this</p></li><li s=
tyle=3D"margin: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D"color:=
 rgb(54,55,55);line-height: 26px;margin-bottom: 0;box-sizing: border-box;pad=
ding-left: 4px;font-size: 16px;margin: 0;">Sponsor, Shed obesity care</p></l=
i><li style=3D"margin: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D=
"color: rgb(54,55,55);line-height: 26px;margin-bottom: 0;box-sizing: border-=
box;padding-left: 4px;font-size: 16px;margin: 0;">Breaking news changed ever=
ything</p></li><li style=3D"margin: 8px 0 0 32px;mso-special-format: bullet;=
"><p style=3D"color: rgb(54,55,55);line-height: 26px;margin-bottom: 0;box-si=
zing: border-box;padding-left: 4px;font-size: 16px;margin: 0;">OTP semagluti=
de exclusive</p></li><li style=3D"margin: 8px 0 0 32px;mso-special-format: b=
ullet;"><p style=3D"color: rgb(54,55,55);line-height: 26px;margin-bottom: 0;=
box-sizing: border-box;padding-left: 4px;font-size: 16px;margin: 0;">DDC lis=
t explained</p></li><li style=3D"margin: 8px 0 0 32px;mso-special-format: bu=
llet;"><p style=3D"color: rgb(54,55,55);line-height: 26px;margin-bottom: 0;b=
ox-sizing: border-box;padding-left: 4px;font-size: 16px;margin: 0;">Novo=E2=80=
=99s lab findings</p></li><li style=3D"margin: 8px 0 0 32px;mso-special-form=
at: bullet;"><p style=3D"color: rgb(54,55,55);line-height: 26px;margin-botto=
m: 0;box-sizing: border-box;padding-left: 4px;font-size: 16px;margin: 0;">30=
2% dose shocker</p></li><li style=3D"margin: 8px 0 0 32px;mso-special-format=
: bullet;"><p style=3D"color: rgb(54,55,55);line-height: 26px;margin-bottom:=
 0;box-sizing: border-box;padding-left: 4px;font-size: 16px;margin: 0;">Cata=
lent=E2=80=99s contamination mess</p></li><li style=3D"margin: 8px 0 0 32px;=
mso-special-format: bullet;"><p style=3D"color: rgb(54,55,55);line-height: 2=
6px;margin-bottom: 0;box-sizing: border-box;padding-left: 4px;font-size: 16p=
x;margin: 0;">Lilly=E2=80=99s B12 tirzepatide bombshell</p></li><li style=3D=
"margin: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D"color: rgb(54=
,55,55);line-height: 26px;margin-bottom: 0;box-sizing: border-box;padding-le=
ft: 4px;font-size: 16px;margin: 0;">Is the molecule changing?</p></li><li st=
yle=3D"margin: 8px 0 0 32px;mso-special-format: bullet;"><p style=3D"color: r=
gb(54,55,55);line-height: 26px;margin-bottom: 0;box-sizing: border-box;paddi=
ng-left: 4px;font-size: 16px;margin: 0;">New oral GLP-1 contender</p></li></=
ul><a class=3D"audio-embed-static-outer" href=3D"https://substack.com/redire=
ct/06cf6d5f-9a89-4438-99ee-7c46de41589a?j=3DeyJ1IjoiNGl3b2U2In0.sVDxRtmZ85v8=
kfdamY0krRXGMy3p768BWtuZifRB-Zs" target=3D"_blank" data-component-name=3D"Au=
dioEmbedStaticLink" style=3D"text-decoration: none;"><table class=3D"audio-e=
mbed-static" cellspacing=3D"12" data-component-name=3D"AudioEmbedStaticTable=
" style=3D"width: 100%;min-width: 100%;min-height: 96px;border: 1px solid rg=
b(0,0,0,.1);background: rgb(255,255,255);margin: 32px 0;border-radius: 12px;=
"><tbody><tr><td class=3D"thumbnail-container" style=3D"padding: 0;margin: 0=
;width: 88px;height: 88px;border-radius: 12px;overflow: hidden;vertical-alig=
n: top;"><div class=3D"play-container" style=3D"font-size: 16px;line-height:=
 26px;max-height: 0;position: relative;opacity: 0.999;z-index: 1;"><img clas=
s=3D"play" src=3D"https://substackcdn.com/image/fetch/$s_!nPrE!,w_72,c_limit=
,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack.com%2Fimg%2Ft=
humbnail-play.png" height=3D"36" width=3D"36" style=3D"border: none !importa=
nt;vertical-align: middle;-ms-interpolation-mode: bicubic;max-width: 100%;di=
splay: inline-block;height: 40px;margin: 24px;width: 40px;" data-unique-iden=
tifier=3D""></div><img class=3D"thumbnail" src=3D"https://i.scdn.co/image/ab=
6765630000ba8a83eb6066245127359ba69bd2" height=3D"80" width=3D"80" style=3D"=
border: none !important;vertical-align: middle;display: block;-ms-interpolat=
ion-mode: bicubic;max-width: 100%;margin: 0 auto;height: 88px;width: 88px;" d=
ata-unique-identifier=3D""></td><td class=3D"audio-details" data-component-n=
ame=3D"AudioEmbedStatic" style=3D"font-family: 'SF Pro Display', -apple-syst=
em, system-ui, BlinkMacSystemFont, 'Inter', 'Segoe UI', Roboto, Helvetica, A=
rial, sans-serif, 'Apple Color Emoji', 'Segoe UI Emoji', 'Segoe UI Symbol';-=
webkit-font-smoothing: antialiased;-moz-osx-font-smoothing: antialiased;-web=
kit-appearance: optimizelegibility;-moz-appearance: optimizelegibility;appea=
rance: optimizelegibility;letter-spacing: -0.012em;text-decoration: none;"><=
p class=3D"title" style=3D"line-height: 20px;margin: 0 0 2px;color: rgb(54,5=
5,55);font-size: 16px;font-weight: 700;">MASSIVE: Compound Tirzepatide and S=
emaglutide Updates!</p><p class=3D"subtitle" style=3D"font-family: 'SF Pro D=
isplay',-apple-system-headline,system-ui,-apple-system,BlinkMacSystemFont,'S=
egoe UI',Roboto,Helvetica,Arial,sans-serif,'Apple Color Emoji','Segoe UI Emo=
ji','Segoe UI Symbol';-webkit-font-smoothing: antialiased;-moz-osx-font-smoo=
thing: antialiased;-webkit-appearance: optimizelegibility;-moz-appearance: o=
ptimizelegibility;appearance: optimizelegibility;font-weight: 400;margin: 0 0=
 2px;color: rgb(119,119,119);line-height: 20px;font-size: 14px;">Dave Knapp G=
LP-1 Industry Insider</p><p class=3D"metadata" style=3D"line-height: 20px;ma=
rgin: 0 0 2px;color: rgb(119,119,119);font-size: 14px;font-weight: 400;">Epi=
sode</p></td></tr></tbody></table></a><p style=3D"margin: 0 0 20px 0;color: r=
gb(54,55,55);line-height: 26px;font-size: 16px;"></p><p style=3D"margin: 0 0=
 20px 0;color: rgb(54,55,55);line-height: 26px;font-size: 16px;">Do you trus=
t compounded GLP-1s based on real-world experience, or do findings like the o=
nes discussed today change your perspective?</p><p class=3D"button-wrapper" d=
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HAiOjE3NzYzNjk4MzcsImlzcyI6InB1Yi00ODA4OTkzIiwic3ViIjoicG9zdC1yZWFjdGlvbiJ9.=
4FdZ13daXSmGuPszO3d4QzWunm0kf5Rxwvk3vqNIuiI&amp;r=3D4iwoe6&amp;utm_campaign=3D=
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0px;font-weight: 600;text-align: center;margin: 0;opacity: 1;outline: none;w=
hite-space: nowrap;color: #ffffff !important;text-decoration: none !importan=
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